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E-book

Title Advances and avenues in the development of novel carriers for bioactives / edited by Manju Rawat Singh [and others]
Published London : Academic Press, 2020

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Description 1 online resource
Contents Front Cover -- Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents -- Copyright Page -- Contents -- List of Contributors -- 1 Challenges and need of delivery carriers for bioactives and biological agents: an introduction -- 1.1 Introduction -- 1.2 Bioactives and biological agents -- 1.2.1 Phytoactives -- 1.2.2 Bioactive peptides -- 1.2.3 Bioactive lipids -- 1.2.4 Micronutrients -- 1.3 Therapeutic significance of bioactives -- 1.4 Need and challenges of delivery carriers for bioactives -- 1.4.1 Challenges in phytoactive delivery
1.4.2 Challenges in protein and peptides delivery -- 1.4.2.1 Chemical modification -- 1.4.2.2 Delivery system -- 1.4.3 Challenges in vitamins delivery -- 1.5 Application of nanotechnology for the delivery of bioactives -- 1.5.1 Nanodelivery carriers for phytoactives or phytomedicines -- 1.5.1.1 Liposomes -- 1.5.1.1.1 Anticancer phytoactives -- 1.5.1.1.2 Antimicrobial phytomedicines -- 1.5.1.2 Niosomes -- 1.5.1.2.1 Antitumor phytoactive -- 1.5.1.2.2 Antiinflammatory phytoactive -- 1.5.1.3 Solid lipid nanoparticles -- 1.5.1.4 Polymeric nanoparticles -- 1.5.1.5 Metal-based nanoparticles
1.5.2 Nanodelivery carrier for bioactive peptides/protein -- 1.5.2.1 Vaccines delivery -- 1.5.2.2 Hormone delivery: insulin -- 1.5.2.3 Enzyme delivery: digestive enzymes -- 1.5.2.4 Antimicrobial delivery -- 1.6 Toxicity and safety concern -- 1.7 Conclusion -- Declaration of interest -- References -- 2 Natural product-based nanomedicine: polymeric nanoparticles as delivery cargoes of food bioactives and nutraceuticals for ... -- 2.1 Problems with anticancer treatment -- 2.1.1 Tumor size -- 2.1.2 Toxicity -- 2.1.3 Hair loss -- 2.1.4 Nausea and vomiting -- 2.1.5 Leukopenia -- 2.1.6 Mucositis
2.1.7 Drug resistance -- 2.1.8 Tumor stem cells -- 2.2 Overcoming drug resistance -- 2.3 Bioactive molecules found in functional foods and nutraceuticals: antitumor activity and chemotherapy treatment improvement -- 2.3.1 Caffeine -- 2.3.2 Catechins -- 2.3.3 Theobromine -- 2.3.4 Capsaicin -- 2.3.5 Sulforaphane -- 2.3.6 Apigenin -- 2.3.7 Resveratrol -- 2.4 Nanotechnology: an alternative way to improve natural products antitumor capacity through better molecules delivery -- 2.5 Physiological barriers: challenges for natural products target delivery
2.6 Polymeric nanoparticles: use in the oncological area for the delivery of bioactive molecules -- References -- Further reading -- 3 The promising expedition of the delivery systems for monoclonal antibodies -- 3.1 Introduction -- 3.2 Monoclonal antibodies -- 3.2.1 Origins/types of monoclonal antibodies -- 3.2.2 Production methodologies -- 3.2.3 Functions and therapeutic applications of monoclonal antibodies -- 3.2.4 Checkpoints blockade monoclonal antibodies -- 3.3 Classic delivery systems for monoclonal antibodies
Notes Includes index
Subject Drug carriers (Pharmacy)
Biomedical materials.
Drug Carriers
Biomedical materials
Drug carriers (Pharmacy)
Form Electronic book
Author Singh, Manju Rawat
ISBN 9780128199183
0128199180