Description |
1 online resource (x, 192 pages) : illustrations |
Series |
Special publication ; no. 279 |
|
Special publication (Royal Society of Chemistry (Great Britain)) ; no. 279.
|
Contents |
Molecular informatics : sharpening drug design's cutting edge -- High-throughput X-ray crystallography for drug discovery -- Trawling the genome for G protein-coupled receptors : the importance of integrating bioinformatic approaches -- Virtual screening of virtual libraries : an efficient startegy for lead generation -- Virtual techniques for lead optimisation -- The impact of physical organic chemistry on the control of drug-like properties -- Mutagenesis and modelling highlight the critical nature of the TM2-loop-TM3 region of biogenic amine GPCRs -- Computational vaccine design |
Summary |
Pharmaceutical research draws on increasingly complex techniques to solve the challenges of drug design. Bringing together a number of the latest informatics techniques, this book looks at modelling and bioinformatic strategies; structural genomics and X-ray crystallography; virtual screening; lead optimisation; ADME profiling and vaccine design. A number of relevant case studies, focussing on techniques that have demonstrated their use, will concentrate on G-protein coupled receptors as potential disease targets. Providing details of state-of-the-art research, Drug Design: Cutting Edge Approaches will be invaluable to all drug discovery scientists, including medicinal and combinatorial chemists, molecular modellers, bio- and chemoinformaticians, and pharmacologists, amongst others |
Analysis |
drug design |
|
medicinal chemistry |
|
RSC |
|
BMCS |
|
MMG |
Notes |
"The proceedings of the meeting on Cutting Edge Approaches to Drug Design held on 13 March 2001 at the Scientific Societies Lecture Theatre, London, UK"--Title page verso |
Bibliography |
Includes bibliographical references and index |
Notes |
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL |
|
English |
|
Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force. WlAbNL |
|
Print version record |
|
digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL |
Subject |
Drugs -- Design -- Congresses
|
|
Drugs -- Design -- Mathematical models -- Congresses
|
|
Artificial intelligence -- Medical applications -- Congresses
|
|
Drugs -- Research -- Methodology -- Congresses
|
|
Mathematical models.
|
|
Pharmaceutical technology.
|
|
Pharmaceutical chemistry.
|
|
Pharmacology.
|
|
Chemistry.
|
|
Physical sciences.
|
|
Life sciences.
|
|
Drugs -- Design.
|
|
Methodology.
|
|
Chemical models.
|
|
Molecular pharmacology -- Computer simulation
|
|
Pharmacology, Experimental -- Computer simulation
|
|
Computer simulation.
|
|
Digital computer simulation.
|
|
Drug Discovery
|
|
Investigative Techniques
|
|
Publication Formats
|
|
Models, Theoretical
|
|
Computing Methodologies
|
|
Technology, Pharmaceutical
|
|
Publication Characteristics
|
|
Analytical, Diagnostic and Therapeutic Techniques and Equipment
|
|
Chemistry, Pharmaceutical
|
|
Information Science
|
|
Pharmacology
|
|
Chemistry
|
|
Natural Science Disciplines
|
|
Biological Science Disciplines
|
|
Disciplines and Occupations
|
|
Drug Design
|
|
Combinatorial Chemistry Techniques
|
|
Methods
|
|
Congresses
|
|
Models, Chemical
|
|
Computer Simulation
|
|
mathematical models.
|
|
pharmacology.
|
|
chemistry.
|
|
physical sciences.
|
|
biological sciences.
|
|
methodology.
|
|
simulation.
|
|
Chemistry.
|
|
MEDICAL -- Drug Guides.
|
|
MEDICAL -- Nursing -- Pharmacology.
|
|
MEDICAL -- Pharmacology.
|
|
MEDICAL -- Pharmacy.
|
|
Science.
|
|
Physical sciences
|
|
Pharmacology
|
|
Pharmaceutical technology
|
|
Pharmaceutical chemistry
|
|
Methodology
|
|
Mathematical models
|
|
Life sciences
|
|
Digital computer simulation
|
|
Computer simulation
|
|
Chemistry
|
|
Chemical models
|
|
Artificial intelligence -- Medical applications
|
|
Drugs -- Design
|
|
Drugs -- Research -- Methodology
|
Genre/Form |
proceedings (reports)
|
|
Conference papers and proceedings
|
|
Conference papers and proceedings.
|
|
Actes de congrès.
|
Form |
Electronic book
|
Author |
Flower, Darren R.
|
LC no. |
2006270060 |
ISBN |
0854048162 |
|
9780854048168 |
|
9781847550705 |
|
1847550703 |
|
1601190271 |
|
9781601190277 |