| Description |
1 online resource |
| Contents |
An introduction to the human tissue microbiome. The human microbiota / Michael Wilson -- An introduction to microbial dysbiosis / Mike Curtis -- The gut microbiota / Herve M Blottiere, Joel Dore -- The oral microbiota / William G Wade -- The skin microbiota / Patrick LJM Zeeuwen, Joost Schalkwijk -- Metagenomic analysis of the human microbiome / Luis G Bermudez-Humaran -- Microbiota-microbiota and microbiota-host interactions in health and disease. Systems biology of bacteria-host interactions / Almut Heinken, Dmitry A Ravcheev, Ines Thiele -- Bacterial biofilm formation and immune evasion mechanisms / Jessica Snowden -- Co-evolution of microbes and immunity and its consequences for modern day life / Markus B Geuking -- How viruses and bacteria have shaped the human genome / Frank Ryan -- The microbiota as an epigenetic control mechanism / Boris A Shenderov -- The emerging role of propionibacteria in human health and disease / Holger Bruggemann -- Dysbioses and bacterial diseases. The periodontal diseases / Luigi Nibali -- The polymicrobial synergy and dysbiosis model of periodontal disease pathogenesis / George Hajishengallis, Richard J Lamont -- New paradigm in the relationship between periodontal disease and systemic diseases / Kazuhisa Yamazaki -- The vaginal microbiota in health and disease / S Tariq Sadiq, Phillip Hay -- Dysbioses and chronic diseases. Reactive arthritis / John D Carter -- Rheumatoid arthritis / Jacqueline Detert -- Inflammatory bowel disease and the gut microbiota / Nik Ding, Ailsa Hart -- Ankylosing spondylitis, Klebsiella and the low-starch diet / Alan Ebringer, Taha Rashid, Clyde Wilson -- Microbiome of chronic plaque psoriasis / Lionel Fry -- Liver disease / Katharina Brandl, Bernd Schnabl -- The gut microbiota / Frida Fak -- The microbiota and susceptibility to asthma / Olawale Salami, Benjamin J Marsland -- Microbiome and cancer / Ralph Francescone, Debora B Vendramini-Costa -- Colorectal cancer and the microbiota / Iradj Sobhani, Severine Couffin -- The gut microbiota and the CNS / Aadil Bharwani, Paul Forsythe -- Genetic dysbiosis / Luigi Nibali -- Mirroring the future. Diet and dysbiosis / Mehrbod Estaki, Candice Quin, Deanna L Gibson -- Probiotics and prebiotics / Marie Jose Butel, Anne-Judith Waligora Dupriet -- The microbiota as target for therapeutic intervention in pediatric intestinal diseases / Andrea Lo Vecchio, Alfredo Guarino -- Microbial therapy for cystic fibrosis / Eugenia Bruzzese, Vittoria Buccigrossi, Giusy Ranucci, Alfredo Guarino |
| Summary |
Microbiota-associated pathology can be a direct result of changes in general bacterial composition, such as might be found in periodontitis and bacterial vaginosis, and/or as the result of colonization and/or overgrowth of so called keystone species. The disruption in the composition of the normal human microbiota, or dysbiosis, plays an integral role in human health and human disease. The Human Microbiota and Human Chronic Disease: Dysbioses as a Cause of Human Pathology discusses the role of the microbiota in maintaining human health. The text introduces the reader to the biology of microbial dysbiosis and its potential role in both bacterial disease and in idiopathic chronic disease states. Divided into five sections, the text delineates the concept of the human bacterial microbiota with particular attention being paid to the microbiotae of the gut, oral cavity and skin. A key methodology for exploring the microbiota, metagenomics, is also described. The book then shows the reader the cellular, molecular and genetic complexities of the bacterial microbiota, its myriad connections with the host and how these can maintain tissue homeostasis. Chapters then consider the role of dysbioses in human disease states, dealing with two of the commonest bacterial diseases of humanity - periodontitis and bacterial vaginosis. The composition of some, if not all microbiotas can be controlled by the diet and this is also dealt with in this section. The discussion moves on to the major 'idiopathic' diseases afflicting humans, and the potential role that dysbiosis could play in their induction and chronicity. The book then concludes with the therapeutic potential of manipulating the microbiota, introducing the concepts of probiotics, prebiotics and the administration of healthy human faeces (faecal microbiota transplantation), and then hypothesizes as to the future of medical treatment viewed from a microbiota-centric position.-Provides an introduction to dysbiosis, or a disruption in the composition of the normal human microbiota -Explains how microbiota-associated pathology and other chronic diseases can result from changes in general bacterial composition -Explores the relationship humans have with their microbiota, and its significance in human health and disease -Covers host genetic variants and their role in the composition of human microbial biofilms, integral to the relationship between human health and human disease Authored and edited by leaders in the field, The Human Microbiota and Human Chronic Disease will be an invaluable resource for clinicians, pathologists, immunologists, cell and molecular biologists, biochemists, and system biologists studying cellular and molecular bases of human diseases |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record and CIP data provided by publisher |
| Subject |
Human body -- Microbiology.
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Chronic diseases.
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Human beings.
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Humans
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Dysbiosis -- complications
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Microbiota -- physiology
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Chronic Disease
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Dysbiosis -- microbiology
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Homo sapiens (species)
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Chronic diseases
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Human body -- Microbiology
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Cos humà.
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Microbiologia.
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Malalties cròniques.
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| Genre/Form |
Llibres electrònics.
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| Form |
Electronic book
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| Author |
Henderson, Brian (Professor), editor.
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Nibali, Luigi, 1978- editor.
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| LC no. |
2016025000 |
| ISBN |
9781118982891 |
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1118982894 |
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9781118982884 |
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1118982886 |
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9781118982907 |
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1118982908 |
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1118982878 |
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9781118982877 |
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