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Title Cellular endocrinology in health and disease / edited by Alfredo Ulloa-Aguirre, P. Michael Conn
Published London : Academic Press, 2014

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Description 1 online resource
Contents Hypothyroidism Retards Tumor Growth but Increases Metastasis DevelopmentDivergent Effects of TRs on Normal and Transformed Cell Proliferation; Acknowledgements; References; 2 The Molecular Cell Biology of Anterior Pituitary Cells; Introduction; Anterior Pituitary: Organization, Cell Types, Hormones and Functions; Diseases of the Anterior Pituitary; Hypopituitarism; ACTH Deficiency; TSH Deficiency; LH, FSH Deficiencies; GH Deficiency; PRL Deficiency; Hyperpituitarism; Prolactinoma; Corticotropinoma; Somatotropinoma; Null Cell Adenomas; Gonadotrophic Adenomas; Thyrotrophic Adenomas
Phenotypic Profile of Anterior Pituitary Cell Types: Different, Yet Somewhat SimilarHeterogeneity within Anterior Pituitary Cell Types: Similar, Yet Somewhat Different; Patterns of Anterior Pituitary Cell Signaling and Secretion; Molecular Mechanisms Underlying Excitability and Basal Secretion; Receptor-Modulated Hormone Release and Voltage-Gated Ca2+ Influx through cAMP-Dependent Pathways; Receptor-Modulated Hormone Release through Ca2+-Mobilizing Pathways; Paracrine (Local) Regulation and Intercellular Signaling within the Anterior Pituitary
Plasticity of Anterior Pituitary Cell Network Organization and FunctionConcluding Remarks; Acknowledgements; References; 3 Sensing Calcium Levels: The Biology of the Parathyroid Cell; Introduction; Biosynthesis and Metabolism of PTH; Regulation of PTH Secretion and Transcription; Calcium-Sensing Properties of the Parathyroids: The CaSR; Phospate/FGF23 Regulation of the Parathyroids; Vitamin D Regulation of the Parathyroids; Main Mechanisms of Parathyroid Gland Hyperplasia in SHPT; Conclusions; References; 4 The Biology of Pituitary Stem Cells; Introduction
Location of Proliferating and Differentiating Cells During Pituitary DevelopmentStrategies for Identifying Pituitary Progenitors; Chromophobes Can Differentiate into All Anterior Pituitary Hormone-producing Cells; Pituitary Progenitors Absorb a Fluorescent Dipeptide and Have Folliculostellate Cell Characteristics; Pituitary Progenitors in the Side Population That Exhibit Rapid Hoechst Dye Efflux; Pituitary Progenitors in the SOX2-Positive Cell Population; Pituitary Progenitors Expressing GFRa2 and PROP1: Rodent and Human; Nestin-GFP Tagged Pituitary Progenitors
Summary Cellular Endocrinology in Health and Disease describes the underlying basis of endocrine function, providing an important tool to understand the fundamentals of endocrine diseases. Delivering a comprehensive review of the basic science of endocrinology, from cell biology to human disease, this work explores and dissects the function of a number of cellular systems. Among these are those whose function was not obvious until recently, including the endocrine functions of bone and the adipose tissue. Providing content that crosses disciplines, Cellular Endocrinology in Health
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Endocrinology.
Endocrine Glands -- cytology
Endocrine System Diseases -- physiopathology
Endocrinology
MEDICAL -- Physiology.
SCIENCE -- Life Sciences -- Human Anatomy & Physiology.
Endocrinology
Form Electronic book
Author Ulloa-Aguirre, Alfredo
Conn, P. Michael
ISBN 130644795X
9781306447959
0124081347
9780124081345
9780124167124
0124167128