A signal-transducing adaptor protein that associates with TNF RECEPTOR complexes. It contains a death effector domain that can interact with death effector domains found on INITIATOR CASPASES such as CASPASE 8 and CASPASE 10. Activation of CASPASES via interaction with this protein plays a role in the signaling cascade that leads to APOPTOSIS
A tumor necrosis factor receptor subtype found in a variety of tissues and on activated LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. Mutations in the CD95 gene are associated with cases of autoimmune lymphoproliferative syndrome
Intracellular signaling adaptor proteins that contain DEATH EFFECTOR DOMAINS and bind to the cytoplasmic DEATH DOMAIN region found on DEATH DOMAIN RECEPTORS. Many of the proteins in this class take part in intracellular signaling involving TUMOR NECROSIS FACTOR RECEPTORS
Intracellular signaling adaptor proteins that contain DEATH EFFECTOR DOMAINS and bind to the cytoplasmic DEATH DOMAIN region found on DEATH DOMAIN RECEPTORS. Many of the proteins in this class take part in intracellular signaling involving TUMOR NECROSIS FACTOR RECEPTORS
Rare congenital lymphoid disorder due to mutations in certain Fas-Fas ligand pathway genes. Known causes include mutations in FAS, TNFSF6, NRAS, CASP8, and CASP10 proteins. Clinical features include LYMPHADENOPATHY; SPLENOMEGALY; and AUTOIMMUNITY
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fas Receptor : Fas signaling / [edited by] Harald Wajant
A tumor necrosis factor receptor subtype found in a variety of tissues and on activated LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. Mutations in the CD95 gene are associated with cases of autoimmune lymphoproliferative syndrome
Fascia -- embryology : Laparoscopic colorectal cancer surgery : Operative Procedures Based on the Embryological Anatomy of the Fascial Composition / Makio Mike
Fasciae (Anatomy) -- Diseases -- Physical therapy : Mobilizing the myofascial system : a clinical guide to assessment and treatment of myofascial dysfunctions / Doreen Killens, BScPT, FCAMPT, CGIMS ; forewords: Diane Lee, BSR, FCAMT, CGIMS, Thomas W Myers, BetsyAnn Baron, BCSI, IASI, FQM
2018
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Fasciae (Anatomy) -- Diseases -- Treatment : Fascial dysfunction : manual therapy approaches / editor, Leon Chaitow, ND, DO (State Registered Osteopathic Practitioner (UK), Honorary Fellow and formerly Senior Lecturer, University of Westminster, London, UK ; Editor-in-Chief, Journal of Bodywork and Movement Therapies ; Director, Ida P Rolf Research Foundation (USA) ; Member Standing Committees, Fascia Research Congress & Fascia Research Society (USA) ; forewords, Thomas W. Findley, MD, PhD, John Sharkey, MSc
2018
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Fasciae (Anatomy) Inflammation -- See Also the narrower term Fibromyalgia
A general term encompassing lower MOTOR NEURON DISEASE; PERIPHERAL NERVOUS SYSTEM DISEASES; and certain MUSCULAR DISEASES. Manifestations include MUSCLE WEAKNESS; FASCICULATION; muscle ATROPHY; SPASM; MYOKYMIA; MUSCLE HYPERTONIA, myalgias, and MUSCLE HYPOTONIA
A general term encompassing lower MOTOR NEURON DISEASE; PERIPHERAL NERVOUS SYSTEM DISEASES; and certain MUSCULAR DISEASES. Manifestations include MUSCLE WEAKNESS; FASCICULATION; muscle ATROPHY; SPASM; MYOKYMIA; MUSCLE HYPERTONIA, myalgias, and MUSCLE HYPOTONIA