| Description |
1 online resource (viii, 190 pages) : illustrations (some color) |
| Series |
Current topics in environmental health and preventive medicine, 2364-8333 |
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Current topics in environmental health and preventive medicine, 2364-8333
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| Contents |
Intro; Preface; Contents; Part I: Overview; Chapter 1: Historical Lessons on Cadmium Environmental Pollution Problems in Japan and Current Cadmium Exposure Situation; 1.1 Historical Lessons from the Cadmium Environmental Pollution Problems in Japan; 1.1.1 Introduction; 1.1.2 Discovery of Cd Environmental Pollution: Dr. Kinichi Yoshioka's Performance Re-evaluation; 1.1.3 Background Information and Significance of Environmental Administration that Led to the Formulation of the Ministry of Health and Welfare's Opinion: Retrospection from the Viewpoint of Regulatory Science |
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1.1.4 Trends and Issues Related to Cd Research in Japan1.1.4.1 Regarding "Cadmium Studies in Japan-A Review" [14]; 1.1.4.2 Regarding "Interim Summary Report on Studies of Health Effects of Cadmium" [15] and "Cd Environmental Pollution Regional Resident Health Survey" Report [15]; 1.2 Current Situation of Japanese People's Exposure to Cd; References; Part II: Health Effects of Cadmium in Human Populations and its Relation to Cadmium Exposure Levels |
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Chapter 2: Recent Clinical and Epidemiological Studies of Itai-Itai Disease (Cadmium-Induced Renal Tubular Osteomalacia) and Cadmium Nephropathy in the Jinzu River Basin in Toyama Prefecture, Japan2.1 Introduction; 2.2 History and the Recent Social Situation of Itai-Itai Disease and Cd Nephropathy; 2.3 Epidemiology of Itai-Itai Disease and Cd Nephropathy; 2.4 The Mechanism of Cd Nephrotoxicity; 2.5 Pathophysiology of Cd Nephropathy; 2.6 Long-Term Clinical Course and Prognosis in Cd Nephropathy; 2.6.1 An 11-Year Follow-Up Study; 2.6.2 A 27-Year Observational Study |
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2.7 FGF-23 in Cd Nephropathy and Patients with Itai-Itai Disease2.8 Conclusions; References; Chapter 3: Novel Pathological Study of Cadmium Nephropathy of Itai-itai Disease; 3.1 Introduction; 3.2 Materials and Methods; 3.3 Results; 3.3.1 The General Pathological Findings in Itai-itai Disease; 3.3.2 The Additional Study of Renal Tubular and/or Nephron Disorder; 3.4 Discussion; References; Chapter 4: Long-Term Follow-Up Study of Residents Exposed to Cadmium in Kakehashi River Basin, Ishikawa, Japan; 4.1 Outline of Cadmium Pollution in the Kakehashi River Basin |
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4.2 Health Survey of the Residents4.3 Renal Effects; 4.4 Follow-Up Studies; 4.5 Bone Effects; 4.6 Biological Half-Life of Urinary Cd; 4.7 The Benchmark Dose (BMD) Method of U-Cd, Rice Cd Concentration, and Lifetime Cd Intake for Renal Effects; 4.8 Conclusion; References; Chapter 5: Effects of Cadmium Exposure on Life Prognosis; 5.1 Introduction; 5.2 Cd Exposure and Mortality; 5.2.1 Dietary Cd Intake and Mortality; 5.2.2 Urinary Cd Levels and Mortality; 5.2.3 Blood Cd Levels and Mortality; 5.3 Cd-Induced Renal Tubular Dysfunction and Mortality |
| Summary |
This volume focuses on cadmium (Cd) exposure, its effects on human health, the mechanism of Cd accumulation and the development of mitigation technologies. Further, it discusses clinical, epidemiological, agricultural, toxicological, and biochemical aspects of Cd pollution and presents recent biochemical studies on molecular mechanisms of Cd cytotoxicity and cellular transport as well as the mechanism of Cd-induced disturbances in phosphorus (P) metabolism. It also provides insights into the pathophysiology of itai-itai disease, a serious condition caused by Cd pollution. Cadmium -New Aspects in Human Disease, Rice Contamination, and Cytotoxicity- is a valuable resource for scientists involved in heavy metal toxicology, botanical sciences, and regulatory sciences. Addressing the features of Cd pollution in the past and in the present, as well as future perspectives, this is a must-have book for students, researchers and practitioners interested in global and local metal pollution |
| Bibliography |
Includes bibliographical references |
| Notes |
Online resource; title from PDF title page (SpringerLink, viewed February 12, 2019) |
| Subject |
Cadmium -- Toxicology
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Cadmium -- toxicity
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Cadmium Poisoning
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Environmental Exposure
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Oryza -- poisoning
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Food Contamination
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Cadmium -- Toxicology
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| Form |
Electronic book
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| Author |
Himeno, Seiichiro, editor
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Aoshima, Keiko, editor
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| ISBN |
9789811336300 |
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981133630X |
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9811336296 |
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9789811336294 |
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9789811336317 |
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9811336318 |
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