Description |
1 online resource (x, 256 pages) : illustrations (some color) |
Series |
Springer protocols |
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Methods in molecular biology, 1940-6029 ; 1381 |
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Springer protocols (Series)
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Methods in molecular biology (Clifton, N.J.) ; v. 1381
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Contents |
Factors affecting the use of human tissues in biomedical research : implications in the design and operation of a biorepository / Daniel S. Atherton [and others] -- Tissue microdissection / Anja Rabien and Glen Kristiansen -- Tissue microarrays / Ana-Maria Dancau [and others] -- Gene expression analysis in the age of mass sequencing : an introduction / Christian Pilarsky, Lahiri Kanth Nanduri, and Janine Roy -- Quantitative DNA methylation profiling in cancer / Ole Ammerpohl [and others] -- Single-nucleotide polymorphism to associate cancer risk / Victoria Shaw, Katie Bullock, and William Greenhalf -- Exosomes in cancer disease / Margot Zöller -- MicroRNA (miRNA) profiling / Lu Gao and Feng Jiang -- Cancer gene profiling for response prediction / B. Michael Ghadimi and Peter Jo -- Target gene discovery for novel therapeutic agents in cancer treatment / Sanjay Tiwari, Ole Ammerpohl, and Holger Kalthoff -- Application of proteomics in cancer biomarker discovery : GeLC-MS/MS / Pedro R. Cutillas and Tatjana Crnogorac-Jurcevic -- Meta-analysis of cancer gene profiling data / Janine Roy, Christof Winter, and Michael Schroeder -- Reproducible, scalable fusion gene detection from RNA-Seq / Vladan Arsenijevic and Brandi N. Davis-Dusenbery -- Transcriptome sequencing for the detection of chimeric transcripts / Hsueh-Ting Chu |
Summary |
This second edition volume brings together the experiences of leading scientists in the discipline of cancer gene profiling. Because cancer genes can be profiled in many different ways, Cancer Gene Profiling: Methods and Protocols, Second Edition explores different techniques and approaches needed to understand the key stages of cancer development, as using only one technique would be insufficient. This book provides readers with an overview of the state-of-the-art methods that will enable them to perform these experiments, and demonstrates the kind of analysis that is possible in our current biomedical research. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Cancer Gene Profiling: Methods and Protocols, Second Edition is a great resource for any student or practitioner with an interest in cancer gene profiling, and can be used in any well-equipped research laboratory |
Bibliography |
Includes bibliographical references and index |
Subject |
Cancer genes.
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DNA microarrays.
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Neoplasms -- genetics
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Gene Expression Profiling -- methods
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Microarray Analysis -- methods
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Genes, Neoplasm
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Medical genetics.
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Oncology.
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Medical -- Genetics.
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Medical -- Oncology.
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Cancer genes
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DNA microarrays
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Genre/Form |
Laboratory manuals.
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Manuels de laboratoire.
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Form |
Electronic book
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Author |
Grützmann, Robert
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Pilarsky, Christian
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LC no. |
2015958099 |
ISBN |
9781493932047 |
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1493932047 |
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