| Description |
xv, 544 pages : illustrations ; 25 cm |
| Contents |
1. Genes and their expression / Dirk-Jan Kleinjan -- 2. Epigenetic modification of chromatin / Donncha Dunican, Sari Pennings and Richard Meehan -- 3. Population genetics and disease / Donald F. Conrad and Jonathan K. Pritchard -- 4. Mapping common disease genes / Naomi R. Wray and Peter M. Visscher -- 5. Population diversity, genomes and disease / Gianpiero L. Cavalleri and David B. Goldstein -- 6. Study design in mapping complex disease traits / Harry Campbell and Igor Rudan -- 7. Diseases of protein misfolding / Christopher M. Dobson -- 8. Aging and disease / Thomas T. Perls -- 9. The MHC paradigm : genetic variation and complex disease / Adrian P. Kelly and John Trowsdale -- 10. Lessons from single gene disorders / Nicholas D. Hastie -- 11. Environment and disease / A. J. McMichael and K. B. G. Dear -- 12. Contemporary ethico-legal issues in genetics / Renate Gertz, Shawn Harmon and Geoffrey Pradella -- 13. Developmental disorders / Stephen P. Robertson and Andrew O. M. Wilkie -- 14. Genes, environment and cancer / D. Timothy Bishop -- 15. The polygenic basis of breast cancer / Paul D. P. Pharoah and Bruce A. J. Ponder -- 16. TP53 : a master gene in normal and tumor suppression / Pierre Hainaut -- 17. Genetics of colorectal cancer / Susan M. Farrington and Malcolm G. Dunlop -- 18. Genetics of autoimmune disease / John I. Bell and Lars Fugger -- 19. Susceptibility to infectious diseases / Andrew J. Walley and Adrian V. S. Hill -- 20. Inflammatory bowel diseases / Jean-Pierre Hugot -- 21. Genetic anemias / W. G. Wood and D. R. Higgs -- 22. Genetics of chronic disease : obesity / I. Sadal Farooqi and Stephen O'Rahilly -- 23. Type 2 diabetes mellitus / Maik L. McCarthy -- 24. Genetics of coronary heart disease / Rossi Naoumova, Stuart A. Cook, Paul Cook and Timothy J. Aitman -- 25. Genetics of hypertension / B. Keavney and M. Lathrop -- 26. Obstructive pulmonary disease / Bipen D. Patel and David A. Lomas -- 27. Skeletal disorders / Robert A. Colbert -- 28. The genetics of common skin diseases / Jonathan Rees -- 29. Molecular genetics of Alzheimer's disease and other adult-onset dementias / P. H. St George-Hyslop -- 30. Major psychiatric disorders in adult life / Amanda Elkin, Sridevi Kalidindi, Kopal Tandon and Peter McGuffin -- 31. Speech and language disorders / Gabrielle Barnby and Anthony J. Monaco -- 32. Common forms of visual handicap / Alan Wright -- 33. Genetic and environmental influences on hearing impairment / Karen P. Steel -- 34. Pharmacogenomics : clinical applications / Gillian Smith, Mark Chamberlain and C. Roland Wolf |
| Summary |
Presents an up-to-date view of the role of genetics in modern medicine, reflecting the strengths and limitations of a genetic perspective |
| Notes |
Formerly CIP. Uk |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online version of the print title |
|
System requirements: Internet connectivity, World Wide Web browser, and Adobe Acrobat reader |
|
Mode of access: World Wide Web |
| Subject |
Medical genetics.
|
|
Genetic Predisposition to Disease.
|
| Author |
Wright, Alan F., MRC.
|
|
Hastie, Nicholas.
|
|
MyiLibrary.
|
| LC no. |
2006102406 |
| ISBN |
9780521541008 paperback |
|
9780521833394 hardback |
|
0521833396 hardback |
|
052154100X paperback |
|
