| Description |
1 online resource (xix, 414 pages) : illustrations |
| Series |
Lung biology in health and disease ; 218 |
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Lung biology in health and disease ; v. 218.
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| Contents |
1. Introduction to genetics / Eva Halapi and Hakon Hakonarson -- 2. Genetic epidemiology of reduced lung function / Cleo C. van Diemen and H. Marike Boezen -- 3. Gene-environment interaction in asthma / Gerard H. Koppelman and Dirkje S. Postma -- 4. Epistatic interaction, age, and gender effects / Michael Kabesch -- 5. Microarray techniques and data in asthma/chronic obstructive pulmonary disease / Thomas J. Mariani and Marco F. Ramoni -- 6. Mouse models for asthma and mouse asthma genetics / Benoit Piavaux, Antoon J.M. van Oosterout, and Machteld N. Hylkema -- 7. Generation of genetically manipulated mouse lines for the study of asthma / Stephen L. Tilley, Irving C. Allen, and Beverly H. Koller -- 8. Comparative genomics of asthma / Ioannis M. Stylianou [and others] -- 9. Proteomic techniques for asthma and chronic obstructive pulmonary disease research / Megan S. Lim and Kojo S.J. Elenitoba-Johnson -- 10. Linkage to asthma and its intermediate phenotypes / Timothy D. Howard and Juan C. Celedón -- 11. Linkage analysis of spirometric phenotypes and chronic obstructive pulmonary disease / Dawn L. Demeo, Craig P. Hersh, and Edwin K. Silverman -- 12. Fine mapping and whole genome association studies in asthma and chronic obstructive pulmonary disease / Miriam F. Moffatt and William O.C. Cookson -- 13. Association studies in asthma / Ingrid A. Laing and Peter N. Le Souëf -- 14. Association studies in chronic obstructive pulmonary disease / Takeo Ishii and Andrew J. Sandford -- 15. [beta]2- adrenergic receptor polymorphisms and asthmatic phenotypes / Stephen B. Liggett and Ian P. Hall -- 16. Interleukin-13 / Donata Vercelli -- 17. CD14 and toll-like receptors / Stefano Guerra and Fernando D. Martinez -- 18. Pharmacogenetics / Kelan Tantisira and Eugene Bleecker |
| Summary |
Responding to the substantial growth that has taken place in the field over the past decade, this reference provides an in-depth overview of current thought on the genetics and genomics of asthma and COPD in relation to their pathogenesis and treatment. With contributions by an esteemed team of international authorities on the topic, this source spans the latest developments in the utilization of microarray techniques, linkage and association studies, mapping strategies, comparative genetics, microarray techniques, proteomics, and pharmacogenomics |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL |
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Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force. WlAbNL |
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Print version record |
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digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL |
| Subject |
Asthma -- Genetic aspects
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Lungs -- Diseases, Obstructive.
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Asthma -- genetics
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Pulmonary Disease, Chronic Obstructive -- genetics
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MEDICAL -- Pulmonary & Thoracic Medicine.
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HEALTH & FITNESS -- Diseases -- Respiratory.
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Lungs -- Diseases, Obstructive
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Astma.
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CARA.
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Aanleg.
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| Form |
Electronic book
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| Author |
Postma, D. S. (Dirkje S.)
|
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Weiss, Scott T.
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| ISBN |
9781420019728 |
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1420019724 |
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9780429166037 |
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0429166036 |
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