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Title Reverse genetics of RNA viruses : applications and perspectives / [edited by] Anne Bridgen
Published Chichester, West Sussex, UK ; Hoboken, NJ : Wiley - Blackwell, 2012
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Description 1 online resource
Contents Definitions of reverse genetics, +ve, -ve, sense and doubled stranded (DS) RNA viruses / Anne Bridgen -- Coronavirus reverse genetics / Paul Britton -- Hepatitis C and use of reverse genetics in drug design / Natalia Frias Staheli -- Norovirus reverse genetics / Ian Goodfellow -- Rhabdovirus reverse genetics / Klaus Conzelmann -- Modification of measles virus and application to pathogenesis studies / Paul Duprex -- Bunyavirus reverse genetics and application to interaction with host cells / Richard Elliott -- Influenza A virus vaccines / Wendy Barclay -- Bluetongue virus reverse genetics / Mark Boyce -- Reovirus reverse genetics / Rob Hoeben -- Reverse genetics and quasispecies / Marco Vignuzzi -- Summary and perspectives / Anne Bridgen
Summary Reverse genetics, the genetic manipulation of RNA viruses to create a wild-type or modified virus, has led to important advances in our understanding of viral gene function and interaction with host cells. Since many severe viral human and animal pathogens are RNA viruses, including those responsible for polio, measles, rotaviral diarrhoea and influenza infections, it is also an extremely powerful technique with important potential application for the prevention and control of a range of human and animal viral diseases. Reverse Genetics of RNA Viruses provides a comprehensive
Bibliography Includes bibliographical references and index
Notes Print version record and CIP data provided by publisher
Subject RNA viruses -- Genetic aspects
Reverse genetics.
Viral vaccines.
RNA Viruses -- genetics
Reverse Genetics -- methods
RNA, Viral -- genetics
Viral Proteins -- genetics
Viral Vaccines
Reverse Genetics
SCIENCE -- Life Sciences -- Biology.
SCIENCE -- Life Sciences -- Microbiology.
Viral vaccines
Reverse genetics
Form Electronic book
Author Bridgen, Anne, 1961-
LC no. 2012017805
ISBN 9781118405345
111840534X
9781118405352
1118405358
9781118405369
1118405366
9781118405338
1118405331