Description |
1 online resource |
Series |
Topics in current chemistry ; 288 |
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Topics in current chemistry ; 288.
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Contents |
Carbohydrate receptors of bacterial adhesins: Implications and reflections / K. Ohlsen [and others] -- Ins and outs of microbial adhesion / M. Virji -- Architectures of multivalent glycomimetics for probing carbohydrate-lectin interactions / M. Lahmann -- Structure, function, and assembly of type 1 fimbriae / S. Knight and J. Bouckaert -- The multiple carbohydrate binding specificities of helicobacter pylori / S. Teneberg -- Bitter sweetness of complexity / A. Horst and C. Wagener -- Staphylococcus epidermidis biofilms: Functional molecules, relation to virulence, and vaccine potential / D. Mack [and others] |
Summary |
Bacterial carbohydrate recognition are conveyed, covering Gram-positive as well as Gram-negative bacteria, in Chapter 4 Streptococci and Staphylococci, and in Chapter 5, carbohydrate binding specificities of Helicobacter pylori. In Chapter 6, "Bitter sweetness of complexity," the collected reflections on mic- bial adhesion are expanded by a perspective on a broader impact of glycosylation on cellular adhesion, motility and regulatory processes, paralleling the complexity of N-glycan structures on cell surfaces. It highlights particularly how structural details of N-glycans have been causally related to pathological scenarios, with a focus on?(1,6)-N-acetylglucosaminyltransferase. In the final chapter, biofilm formation is reviewed, covering knowledge about structure and biosynthesis of polysaccharide intercellular adhesins (PIAs) which are central to biofilm formation. This comprehensive chapter explains all PIA-related principles of medical device-associated infections. It is our hope, that this collection of expert articles, ranging from structural ch- istry and structural biology to biochemistry and medicine, will be a stimulation and motivation for our colleagues in the life sciences. At the same time, we hope that these reflections on microbial adhesion will awake interest in and promote und- standing of the complex processes associated with the glycocalyx and the multif- eted interactions between the host cell and its "guest," as well as the biological consequences resulting from this mutual interplay |
Bibliography |
Includes bibliographical references and index |
Notes |
English |
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Print version record |
Subject |
Glycoconjugates.
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Microorganisms -- Adhesion.
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Glycosylation.
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Bacterial Adhesion -- physiology
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Glycoconjugates
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Adhesins, Bacterial
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Glycocalyx -- metabolism
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Glycosylation
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Glycoconjugates.
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Microorganisms -- Adhesion.
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Science des matériaux.
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Chimie.
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Glycosylation
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Glycoconjugates
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Microorganisms -- Adhesion
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Adhäsion
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Glykokonjugate
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Kohlenhydrate
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Mikroorganismus
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Zelladhäsion
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Genre/Form |
Aufsatzsammlung.
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Form |
Electronic book
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Author |
Lindhorst, Thisbe K
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Oscarson, Stefan
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ISBN |
9783642013041 |
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364201304X |
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3642013031 |
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9783642013034 |
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1280382775 |
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9781280382772 |
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9786613560681 |
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6613560685 |
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