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Title Gene therapy for renal diseases and transplantation / volume editors, Ariela Benigni, Giuseppe Remuzzi
Published Basel ; New York : Karger, [2008]
©2008
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Description 1 online resource (viii, 167 pages) : illustrations (some color)
Series Contributions to nephrology, 0302-5144 ; v. 159
Contributions to nephrology ; v. 159. 0302-5144
Contents Renal diseases as targets of gene therapy / Phillips, B., Giannoukakis, N., Trucco, M. -- Non-viral gene delivery / Akital, H., Harashima, H -- Retrovirus vectors for gene delivery / Lech, P., Somia N.V -- Adenovirus vectors for renal targeted gene delivery / Appledorn, D.M., Seregin, S., Amalfitano, A. -- Adeno-associated virus vectors: versatile tools for in vivo gene transfer / Zentilin, L., Giacca, M. -- RNA interference in research and therapy of renal diseases / Rácz, Z., Hamar, P -- Gene therapy for acute renal failure / Torras, J., Cruzado, J.M., Grinyo, J.M -- Chronic deteriorating renal function and renal fibrosis / Isaka, Y., Takahara, S., Imai, E. -- Allograft rejection: acute and chronic studies / Tomasoni, S., Remuzzi, G., Benigni, A. -- Gene therapy for renal cancer / Haviv, Y.S., Curiel, D.T -- HIV-associated nephropathy / Wyatt, C.M., Rosenstiel, P.E., Klotman, P.E
Summary Initially conceived as a strategy to remedy inherited genetic disorders, gene therapy has been successfully applied in the last decade to ameliorate the renal function compromised by progressive renal diseases and to prevent kidney allograft rejection in experimental animals. In the present book, world-renowned experts are presenting new insights into viral and non-viral systems used to effect gene delivery, one chapter being dedicated to the new field of RNA interference (RNAi). This latter method may be successfully used in renal ischemia-reperfusion injury, trauma and transplantation. In th
Bibliography Includes bibliographical references and indexes
Notes Print version record
Subject Kidney Diseases -- therapy.
Genetic Therapy.
Graft Rejection -- therapy.
Kidney Transplantation.
Gene therapy.
Graft rejection -- Prevention.
Kidneys -- Diseases -- Gene therapy.
Kidneys -- Transplantation -- Genetic aspects.
Form Electronic book
Author Benigni, Ariela.
Remuzzi, Giuseppe.
ISBN 3805585063
9783805585064