| Description |
1 online resource (xix, 202 pages) : illustrations |
| Contents |
Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals -- Copyright -- Preface -- Contents -- Introduction -- REVIEW OF THE NAC DOCUMENT -- REFERENCES -- Roster National Advisory Committee for Acute Exposure Guideline Levels (NAC/AEGL Committee) for Hazardous Substances -- COMMITTEE MEMBERS -- Past Committee Members -- Participants from Cooperative Partner Countries -- Other Participants -- Oak Ridge National Laboratory Staff -- AEGL Program Senior Staff -- Appendix -- Preface |
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1. Overview of AEGL Program and NAC/AEGL CommitteeHISTORY -- PURPOSE AND OBJECTIVES OF THE AEGL PROGRAM AND THE NAC/AEGL COMMITTEE -- COMMITTEE MEMBERSHIP AND ORGANIZATIONAL STRUCTURE -- SELECTION OF CHEMICALS FOR AEGL DEVELOPMENT -- SCIENTIFIC CREDIBILITY OF AEGL VALUES -- THE AEGL DEVELOPMENT AND PEER-REVIEW PROCESS -- Stage 1: Draft AEGLs -- Stage 2: Proposed AEGLs -- Stage 3: Interim AEGLs -- Stage 4: Final AEGLs -- OPERATION OF THE NAC/AEGL COMMITTEE -- VALUE OF A COLLABORATIVE EFFORT IN THE AEGL PROGRAM -- APPLICATIONS OF THE AEGL VALUES |
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""2. Derivation of AEGL Values""""2.1 CHARACTERIZATION OF AEGLS""; ""2.2 EMPIRICAL TOXICOLOGIC ENDPOINTS AND METHODS FOR DETERMINING EXPOSURE CONCENTRATIONS USED TO DERIVE AEGLS 1, 2, AND 3""; ""2.2.1 Selection of the Highest Exposure Level at Which the Effects That Define an AEGL Are Not Observed""; ""2.2.2 Selection of Health-Effect Endpoints for AEGL-1, AEGL-2, and AEGL-3""; ""2.2.2.1 AEGL-1 Endpoints""; ""2.2.2.1.1 No Value Established�AEGL-1 Is Close to or Exceeds AEGL-2""; ""2.2.2.1.2 No Value Established�Insufficient Data"" |
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""2.2.2.1.3 Highest Experimental Exposure Without an AEGL-1 Effect""""2.2.2.1.4 Effect Level for a Response""; ""2.2.2.2 AEGL-2 Endpoints""; ""2.2.2.2.1 Highest Experimental Exposure Without an AEGL-2 Effect""; ""2.2.2.2.2 Effect Level for a Toxic Response That Was Not Incapacitating or Not Irreversible""; ""2.2.2.2.3 A Fraction of the AEGL-3 Value""; ""2.2.2.3 AEGL-3 Endpoints""; ""2.2.2.3.1 Highest Exposure Level That Does Not Cause Lethality�Experimentally Observed Threshold (AEGL-3 NOAEL)"" |
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""2.2.2.3.2 Highest Exposure Level That Does Not Cause Lethality�Estimated Lethality Threshold�One-Third of the LC50""""2.2.2.3.3 Highest Exposure Level That Does Not Cause Lethality�Benchmark Exposure Calculation of the 5% and 1% Response""; ""2.2.2.3.4 Effect Level for a Response""; ""2.3 GUIDELINES AND CRITERIA FOR THE SEARCH STRATEGY, EVALUATION, SELECTION, AND DOCUMENTATION OF KEY DATA AND SUPPORTING�""; ""2.3.1 Search Strategy""; ""2.3.2 Evaluation, Selection, and Documentation of Key and Supporting Data""; ""2.3.3 Elements for Discussion on Data Adequacy and Research Needs"" |
| Analysis |
Samfundsvidenskab Sociologi |
| Bibliography |
Includes bibliographical references |
| Notes |
Print version record |
| Subject |
Hazardous substances -- Risk assessment -- United States
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Chemicals -- Physiological effect.
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Threshold limit values (Industrial toxicology)
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Hazardous Substances -- toxicity
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Maximum Allowable Concentration
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Risk Assessment -- standards
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HEALTH & FITNESS -- Safety.
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Threshold limit values (Industrial toxicology)
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Chemicals -- Physiological effect
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Hazardous substances -- Risk assessment
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United States
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| Genre/Form |
Electronic books
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| Form |
Electronic book
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| Author |
National Research Council (U.S.)
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| ISBN |
0309570115 |
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9780309570114 |
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