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Title ACEi and ARBS in hypertension and heart failure / Pasquale Perrone Filardi, editor
Published Cham : Springer, 2014
Online access available from:
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Description 1 online resource (x, 150 pages) : illustrations (some color)
Series Current Cardiovascular Therapy ; 5
Current cardiovascular therapy ; 5
Contents Preface; Contents; Contributors; Chapter 1: Angiotensin Converting Enzyme Inhibitors and AT1 Antagonists for Treatment of Hypertension; RAS Inhibition and Blood Pressure Lowering; RAS Inhibition and Hypertension-Related Metabolic Abnormalities; Dyslipidemias; Metabolic Syndrome and Obesity; Insulin Resistance and Diabetes; RAS Inhibition and Hypertension-Related TOD; Left Ventricular Hypertrophy; Chronic Kidney Disease; Dual RAS Inhibition; Atherosclerosis; RAS Inhibition and CV Events; Stroke; Myocardial Infarction; RAS Inhibitors and Mortality; References
Chapter 2: ACE Inhibitor and Renin-Angiotensin System the Cornerstone of Therapy for Systolic Heart Failure; Definition of Heart Failure; Epidemiology, Incidence, Prevalence and Natural History of Heart Failure; Aetiology of Heart Failure; Pathophysiology of Heart Failure; The Renin-Angiotensin System; Focus on Blockade of the Renin-Angiotensin System; Trials That Support the Use of Angiotensing-Converting Enzyme Inhibitors; ACE-Inhibitors Compared with Angiotensin Receptor Blockers; Use of the ACE Inhibitors in the Hearth Failure: ESC and ACCF/AHA Guidelines; References
Chapter 3: Impact of Chronic Kidney Disease and Diabetes Mellitus on Choice of Renin Angiotensin System-Inhibitors in Patients with Hypertension and Heart Failure; Introduction; Choice of RAAS Inhibitors in Patients with Chronic Kidney Disease; Studies in Diabetic or Non-diabetic Proteinuric Kidney Disease; Studies in Non-proteinuric Kidney Disease; High Doses of RAAS-Inhibitors or Dual RAAS Blockade; Choice of Antihypertensive Treatment in Patients with Diabetes Mellitus; Effects of Antihypertensive Agents on Insulin Sensitivity; Effects of Antihypertensive Agents on New-Onset DM
Data from Hypertension Outcome Trials Evaluating New-Onset DM as a Secondary Outcome; Data from Trials and Meta-analyses Investigating the Effects of Antihypertensive Agents on Metabolic Parameters and New-Onset DM; New-Onset DM and Cardiovascular Risk; Conclusion; References; Chapter 4: Target Organ Damage and RAAS Blockade; Introduction; RAAS Dysregulation and Target Organ Damage; Monotherapy with ACEIs; Monotherapy with ARBs; Dual Therapy; Comparison Between ACEIs and ARBs; Conclusions; References; Index
Summary The renin angiotensin system is implicated in the progression of atherosclerotic disease as well as of left ventricular dysfunction. Angiotensin converting enzyme inhibitors and AT1 receptor antagonists have been proven to reduce morbidity and mortality in patients with left ventricular dysfunction or in those at high cardiovascular risk with preserved ventricular function. This book is intended to summarize evidences and provide a rationale for the appropriate use of RAS antagonists in cardiovascular diseases. It will be presented as highly practical information on this topic
Notes Includes index
Online resource; title from PDF title page (SpringerLink, viewed November 4, 2014)
Subject Angiotensin converting enzyme -- Inhibitors.
Heart failure -- Chemotherapy.
Hypertension -- Chemotherapy.
Angiotensin-Converting Enzyme Inhibitors -- therapeutic use.
Form Electronic book
Author Filardi, Pasquale Perrone, editor
ISBN 3319097881 (electronic bk.)
9783319097886 (electronic bk.)