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Book Cover
E-book

Title Heart transplantation : indications & contraindications, procedures & complications / edited by Catherine T. Fleming
Published Hauppauge, N.Y. : Nova Science, ©2009

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Description 1 online resource (xiii, 297 pages) : illustrations
Contents Heart Transplantation: Indications and Contradictions, Procedures and Complications; Contents; Preface; Management of Tricuspid Regurgitation After Cardiac Transplantation; Abstract ; Introduction ; Pathophysiology of Tricuspid Valve Regurgitation Following Cardiac Transplantation ; Management of Refractory Tricuspid Regurgitation ; Recent Experience with Repairs and Replacements ; Repair or Replacement? ; Preventing Post-Transplant TR ; Conclusion ; References ; Virtual Histology Intravascular Ultrasound in Coronary Allograft Vasculopathy; References
Gene Therapy for Prevention of Acute and Chronic Cardiac RejectionAbstract ; 1. Introduction ; 2. Antisense Cyclin-Dependent Kinase (cdk) 2 Kinase ODN ; 3. Antisense Proliferating-Cell Nuclear Antigen (PCNA) ODN ; 4. Antisense Bcl-x ODN; 5. E2F Decoy ; 6. NF-kB Decoy ; 7. Summary ; Acknowledgement; References ; Prevention of Heart Allograft Rejection by Immunotherapy with Ex Vivo-Expanded Foxp3+CD4+CD25+ Natural Regulatory T Cells; Abstract; Introduction ; Overview of Foxp3+CD4+CD25+ nTreg Cells ; Foxp3+CD4+CD25+ Treg Cells and Allograft Rejection
Foxp3+CD4+CD25+ Treg Cells and Allograft Tolerance Rationale for Immunotherapy with Foxp3+CD4+CD25+ nTreg Cells ; Strategies and Procedures for Ex Vivo Expansion of CD4+CD25+ nTreg Cells ; Dynamics of Foxp3 Expression during Ex Vivo Expansion ; Suppressive Activity in MLR Assays ; Engraftment, Trafficking and Homing after Adoptive Transfer ; In Vivo Suppression and Allograft Survival ; Determinants of in Vivo Therapeutic Efficacy; Issues Regarding CD8+CD25+ nTreg Cells ; Generation and Application of Foxp3+CD4+CD25+ iTreg Cells ; Challenges to Clinical Application ; Conclusion
Introduction Direct and Indirect Allorecognition ; Dendritic Cell Subsets and Dendritic Cell Maturation in Organ Transplantation ; Circulating Dendritic Cells in Human Organ Transplantation ; Therapeutic Strategies Based on Genetically Modified Dendritic Cells ; Therapeutic Modulation of Dendritic Cell Chemoattraction; Generation of Regulatory Dendritics Cells ; Pharmacological Dendritic Cell Inhibitors ; Concluding Remarks ; Acknowledgements ; References ; Heart Transplantation: Indications and Contraindications, Procedures and Complications; Abstract ; Introduction ; Epidemiology
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Heart -- Transplantation.
Graft rejection.
Heart Transplantation -- adverse effects
Graft Rejection
Heart Transplantation
Graft rejection
Heart -- Transplantation
Form Electronic book
Author Fleming, Catherine T
ISBN 1608765911
9781608765911