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Title Molecular aspects of the stress response : chaperones, membranes and networks / edited by Peter Csermely, László Vígh
Published New York, N.Y. : Springer Science+Business Media, LLC ; Austin, TX : Landes Bioscience/, [2007]
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Description 1 online resource (xviii, 201 pages) : illustrations, portraits
Series Advances in experimental medicine and biology ; v. 594
Advances in experimental medicine and biology ; v. 594
Contents Protein misassembly: macromolecular crowding and molecular chaperones / R. John Ellis -- The cellular "networking" of mammalian HSP27 and its functions in the control of protein folding, redox state and apoptosis / André-Patrick Arrigo -- Molecular interaction network of the HSP90 chaperone system / Rongmin Zhao and Walid A. Houry -- Organization of the functions and components of the endoplasmic reticulum / Yuichiro Shimizu and Linda M. Hendershot -- Molecular crime and cellular punishment: active detoxification of misfolded and aggregated proteins in the cell by the chaperone and protease networks / Marie-Pierre Hinault and Pierre Goloubinoff -- Chaperones as parts of cellular networks / Peter Csermely, Csaba Söti and Gregory L. Blatch -- Chaperones as parts of organelle networks / György Szabadkai and Rosario Rizzuto -- Heat shock factor 1 as a coordinator of stress and developmental pathways / Julius Anckar and Lea Sistonen -- Chaperone regulation of the heat shock protein response / Richard Voellmy and Frank Boellmann -- Mechanisms of activation and regulation of the heat shock-sensitive signaling pathways / Sébastien Ian Nadeau and Jacques Landry -- Membrane-regulated stress response: a theoretical and practical approach / László Vígh [and others] -- Beyond the lipid hypothesis: mechanisms underlying phenotypic plasticity in inducible cold tolerance / Scott A.L. Hayward [and others] -- Trehalose as a "chemical chaperone:" fact and fantasy / John H. Crowe -- Chaperones as part of immune networks / Zoltán Prohászka -- The stress of misfolded proteins: C. elegans models for neurodegenerative disease and aging / Heather R. Brignull, James F. Morley and Richard I. Morimoto -- HSP90 and developmental networks / Suzannah Rutherford, Jennifer R. Knapp and Peter Csermely
Summary This book is authored by an exciting mixture of top experts and young rising stars from the fields of molecular chaperones and stress adaptation. In addition to giving a comprehensive summary with original references to their field, all authors share their hypotheses and vision on future trends with the reader. The book makes a novel synthesis of the molecular aspects of the stress response and long term adaptation processes with the system biology approach of biological networks. A novel perspective of "old facts" is provided in each chapter, where "old" means only 5-10 years in this rapidly expanding field. The integrative, holistic nature of the book makes it an excellent reading for undergraduates, graduate students and fellow scientists extending their knowledge and studies
Bibliography Includes bibliographical references and index
Notes Print version record
In Springer e-books
Subject Heat shock proteins.
Molecular chaperones.
Protein folding.
Stress (Physiology)
Stress, Physiological -- physiopathology
Heat-Shock Proteins.
Molecular Chaperones.
Protein Folding.
Form Electronic book
Author Csermely, Peter.
Vígh, László, prof.
LC no. 2007295588
ISBN 0387399747