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Book Cover
E-book

Title Heat shock proteins and the brain : implications for neurodegenerative diseases and neuroprotection / edited by Alexzander A.A. Asea, Ian R. Brown
Published Dordrecht ; London : Springer, 2008
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Description 1 online resource
Series Heat shock proteins ; 3
Heat shock proteins (Series) ; 3
Contents pt. 1. Heat shock proteins and neurodegenerative diseases -- pt. 2. Heat shock proteins and neuroprotection -- pt. 3. Extracellular heat shock proteins and the nervous system -- pt. 4. Aging, control of life span and expression of heat shock proteins
Summary With the prevalence of neurodegenerative diseases on the rise as average life expectancy increases, the hunt for effective treatments and preventive measures for these disorders is a pressing challenge. Neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis have been termed 'protein misfolding disorders' that are characterized by the neural accumulation of protein aggregates. Manipulation of the cellular stress response involving the induction of heat shock proteins offers a therapeutic strategy to counter conformational changes in neural
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Heat shock proteins.
Nerve tissue proteins.
Nervous system -- Degeneration.
Neuroprotective agents.
Heat-Shock Proteins -- therapeutic use.
Heat-Shock Proteins -- metabolism.
Nerve Tissue Proteins.
Neurodegenerative Diseases -- drug therapy.
Neuroprotective Agents -- pharmacology.
Form Electronic book
Author Asea, Alexzander A. A.
Brown, Ian R.
ISBN 1402082304
1402082312
9781402082306
9781402082313