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Title Transcription factors : normal and malignant development of blood cells / edited by Katya Ravid, Jonathan D. Licht
Published New York : Wiley-Liss, [2001]
©2001
Online access available from:
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Description 1 online resource (xv, 622 pages) : illustrations
Contents TRANSCRIPTION FACTORS; CONTENTS; Introduction; Contributors; I TRANSCRIPTION FACTORS AND THE MEGAKARYOCYTIC AND ERYTHROID LINEAGES; II TRANSCRIPTION FACTORS AND THE MYELOID LINEAGE; III TRANSCRIPTION FACTORS AND THE LYMPHOID LINEAGE; IV. TRANSCRIPTION FACTORS INVOLVED IN LEUKEMIAS DUE TO CHROMOSOMAL TRANSLOCATION; V. ONCOGENESIS AND HEMATOPOIESIS; VI. SUMMARY OF TRANSCRIPTION FACTORS IMPLICATED IN HEMATOPOIESIS: IN VIVO STUDIES; Index
Summary The role of transcription factors in activating specific genes in blood cells is an important facet of hematopoiesis. Equally important, however, is the pursuit of genes rearranged and aberrantly activated in leukemias (blood malignancies). Transcription Factors: Normal and Malignant Development of Blood Cells focuses on those major transcription factors involved in activation of lineage-specific gene expression during normal versus malignant development of specific blood lineages, as revealed from gene promoter studies, knockout of transcription factors in mice models, and the identification
Bibliography Includes bibliographical references and index
Notes Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL
Print version record
Subject Blood cells.
Hematopoiesis -- Regulations.
Leukemia.
Transcription factors.
Gene Expression Regulation.
Hematopoiesis -- physiology.
Leukemia -- genetics.
Transcription Factors -- physiology.
Transcription, Genetic.
Genre/Form Rules.
Administrative regulations.
Form Electronic book
Author Licht, Jonathan D.
Ravid, Katya.
ISBN 0471223883 (Electronic)
0471461067 (electronic bk.)
9780471223887 (Electronic)
9780471461067 (electronic bk.)
(cloth ; alk. paper)