Title Disorders of blood pressure regulation : phenotypes, mechanisms, therapeutic options / Adel E. Berbari, Giuseppe Mancia, editors

Published Cham, Switzerland : Springer, 2018

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Description 1 online resource Series Updates in hypertension and cardiovascular protection, 2366-4606 Updates in hypertension and cardiovascular protection. Contents Intro; Preface; Contents; Part I: General Aspects; 1: Introduction: Definition and  Classification of  Arterial Pressure Phenotypes; 1.1 Introduction; 1.2 Which Pressure?; 1.3 Classification of  Systemic Arterial Pressure; 1.3.1 Variability of  Blood Pressure; 1.4 Summary; References; 2: Diagnostic and  Prognostic Significance of  Blood Pressure Indices; 2.1 The Physiology of  Individual Blood Pressure Indices; 2.2 Age-Related BP Indices; 2.3 BP Indices in the  US Population by Age and  Sex; 2.4 The Development of  Isolated Systolic Hypertension (ISH) 2.5 Two Pathways for the  Development of  ISH Indices2.6 Value of  BP Indices in the  Diagnosis of  CHD Risk; 2.7 The Value of  Paired BP Indices in Predicting CVD Risk; 2.8 Components of  PP Associated with  Higher CVD Risk; 2.9 Central Pressure and  CVD Risk; 2.10 The Role of  J-Curve BP Indices in Predicting CVD Risk; References; 3: Role of  Circadian Rhythms and  Seasonal Variation in BP Levels; 3.1 Introduction; 3.2 Factors Influencing Circadian Rhythm; 3.3 Seasonal BP Variations; 3.4 Clinical Implications; References 4: Natural History of  Treated and  Untreated Hypertension4.1 Hypertension and  Target Organ Damage; 4.2 Pathophysiology of  Vascular Changes in Hypertension and  Hypertensive (Pheno)Types; 4.3 Defining the  Targets in Hypertension Management; References; Part II: Mechanisms of Hypertension Development; 5: The Kidneys, Volume and  Blood Pressure Regulation, and  Hypertension; 5.1 Introduction; 5.2 Long-Term Regulation of  Extracellular Volume and  Blood Pressure; 5.3 Pressure Natriuresis: A Key Factor in Maintaining Sodium Balance in Hypertension 5.4 Impaired Renal-Pressure Natriuresis in Hypertension Caused by Intra- and  Extrarenal FactorsReferences; 6: Nervous System; 6.1 Methods of  Investigating Sympathetic Activity; 6.1.1 Catecholamines; 6.1.2 Regional Catecholamine Spillover; 6.1.3 Baroreceptor Function Testing; 6.1.4 Spectral Analysis of  Heart Rate Variability; 6.1.5 Microneurography; 6.1.6 Imaging Techniques; 6.2 Sympathetic Influences in the  Blood Pressure Regulation; 6.2.1 Effect of  Sympathetic Activation on Cardiovascular Regulation 6.3 Increased Adrenergic Tone in the  Development of  the  Hypertensive State6.3.1 Increased Adrenergic Tone in the  Progression of  Hypertensive State; 6.4 Mechanisms Leading to Sympathetic Activation and  New Hypothesis; References; 7: Hormonal Systems; 7.1 Introduction; 7.2 The Renin-Angiotensin System; 7.2.1 From Renin to Angiotensin II; 7.2.2 Classical Renin-Angiotensin System; 7.2.3 Clinical Implications; 7.2.4 The Recent Fingerprint of  RAS Peptides; 7.2.5 The Novel 'Protective' Arm of  RAS; 7.3 Aldosterone; 7.3.1 Aldosterone Synthesis; 7.3.2 Primary Aldosteronism Summary This book aims to present a comprehensive classification of hypertensive phenotypes based on underlying target organ involvement. Particular emphasis is placed on review and assessment of clinical presentation, pathophysiologic mechanisms, and possible specific therapeutic options for each hypertension phenotype. Several of these phenotypes are well known and well described in the literature, such as prehypertension, white coat and masked hypertension, isolated systolic hypertension, renovascular hypertension, endocrine hypertension, pediatric hypertension, and gestational hypertension. Other hypertension phenotypes, however, are not widely recognized, being reported only in special reviews; examples include hypertension associated with renal calculus disease and other rarer causes such as Turner syndrome, herbal and medicinal compounds, and pharmacologic agents. A detailed account of the various causes of monogenic hypertension is also included. Finally, a section is devoted to general aspects of hypertension, including the significance of blood pressure indices, the natural course of untreated and treated hypertension, hypertension mechanisms, genetics, and guidelines for blood pressure control Bibliography Includes bibliographical references Notes Online resource; title from PDF title page (EBSCO, viewed February 2, 2018) Subject Hypertension. Hypertension Cardiovascular medicine. Renal medicine & nephrology. Endocrinology. Neurology & clinical neurophysiology. Physiology. HEALTH & FITNESS -- Diseases -- General. MEDICAL -- Clinical Medicine. MEDICAL -- Diseases. MEDICAL -- Evidence-Based Medicine. MEDICAL -- Internal Medicine. Hypertension Form Electronic book Author Berbari, Adel E., editor Mancia, Giuseppe, editor European Society of Hypertension. ISBN 9783319599182 3319599186

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