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Title How the immune system recognizes self and nonself : immunoreceptors and their signaling / Daisuke Kitamura, editor
Published Tokyo ; New York : Springer, [2008]
Online access available from:
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Description 1 online resource (xviii, 251 pages) : illustrations
Contents Recognition of pathogens: toll-like receptors / Satoshi Uematsu, Shizuo Akira -- Strategies of natural killer (NK) cell recognition and their roles in tumor immunosurveillance / C. Andrew Stewart, Eric Vivier -- Recent progress on paired immunoglobulin-like receptors / Hiromi Kubagawa [and others] -- Self-nonself recognition through B-cell antigen receptor / Daisuke Kitamura -- How do T cells discriminate self from nonself? / Catherine Mazza, Bernard Malissen -- Fc receptors / Falk Nimmerjahn, Jeffrey V. Ravetch -- Self and nonself recognition by coreceptors on B lymphocytes: regulation of B lymphocytes by CD19, CD21, CD22, and CD72 / Kozo Watanabe, Takeshi Tsubata -- Co-receptors in the positive and negative regulation of T-cell immunity / Helga Schneider, Christopher E. Rudd
Summary The immune system is a highly evolved security system that protects the body from infection by pathogens such as viruses and bacteria. The immune system also recognizes and rejects a transplanted organ from even the same species. Indeed, the immune system potentially recognizes and eliminates everything that invades the body (nonself). However, it does not normally eliminate self cells or tissues except tumor cells developed from self tissue. Occasionally the immune system breaks down and attacks the body components of the self, manifesting as autoimmune diseases such as rheumatoid arthritis
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Cellular immunity.
Immune recognition.
Immune response.
Immune system.
Receptors, Immunologic -- physiology.
Immunity, Cellular -- physiology.
Lymphocytes -- physiology.
Form Electronic book
Author Kitamura, Daisuke.
ISBN 4431738835 (paper)
9784431738831 (paper)