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E-book

Title Principles of immunopharmacology / edited by Frans P. Nijkamp and Michael J. Parnham
Edition Second revised and extended edition
Published Basel ; Boston : Birkhäuser Verlag, [2005]
©2005
Online access available from:
Springer eBooks    View Resource Record  

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Description 1 online resource (xxiii, 662 pages) : illustrations (some color)
Contents Cover -- Contents -- Preface to the first edition -- Preface to the second edition -- Abbreviations -- A: Mechanisms of immunity -- A.1 Hematopoiesis, including lymphocyte development and maturation -- Introduction: acquisition of specificity -- Hematopoiesis -- T and B lymphocytes: common origin from hematopoietic stem cells -- Specificity: rearrangement of genes encoding antigen receptors -- T lymphocyte maturation in the thymus -- B lymphocyte development in the bone marrow -- Mature T and B lymphocytes: tolerance -- T and B lymphocyte development and maturation: relevance for immunopharmacology -- Summary -- Selected readings -- Recommended website -- References -- A.2 T cell-mediated immunity -- Introduction -- Biology of the T lymphocyte immune response -- Composition of the T cell network -- T cell subset markers -- Effectors of T cell-mediated immunity -- Mechanisms of T cell-mediated cytotoxicity -- Mechanisms of T cell activation -- Tolerance -- Summary -- Selected readings -- A.3 Antibody diversity and B cell-mediated immunity -- Antibodies and immunoglobulins -- Structure of immunoglobulins -- The generation of antibody diversity -- B cell receptor and signal transduction -- B lymphocyte costimulation -- Cytokine regulation -- T cell-independent B lymphocyte activation -- Primary and secondary antibody response -- Biological functions of antibodies -- Clinical relevance and future prospects -- Summary -- Selected readings -- Recommended websites -- References -- A.4 Cytokines -- Introduction -- Differentiation factors -- Activation and growth factors of lymphocytes -- Mediators of inflammation -- Regulatory factors of immune reactions -- Chemokines -- Inhibition of cytokines -- Summary and outlook -- Selected readings -- Recommended website -- References -- A.5 Innate immunity -- phagocytes, natural killer cells and the complement system -- Phagocytes -- Natural killer cells -- The complement system -- Summary -- Selected readings -- References -- A.6 Inflammatory mediators and intracellular signalling -- Introduction -- Eicosanoids -- Platelet-activating factor (PAF) -- Toll-like receptors -- Cytokines -- Chemokines and their intracellular signalling -- Neuropeptides -- Kinins -- Nitric oxide -- Reactive oxygen species -- Amines -- Summary -- Selected readings -- References -- A.7 Immune response in human pathology: infections caused by bacteria, viruses, fungi, and parasites -- Infections -- Natural resistance -- Specific resistance -- Defence against bacteria, viruses, fungi, and parasites -- Pathogenesis of shock -- Human immunodeficiency virus infection -- Vaccines and vaccination -- Infections in the new millennium -- Summary -- Acknowledgements -- Selected readings -- Recommended websites -- A.8 Immune response in human pathology: hypersensitivity and
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Immunopharmacology.
Immunity -- drug effects.
Adjuvants, Immunologic -- pharmacology.
Immunologic Tests.
Immunosuppressive Agents -- pharmacology.
Immunotherapy.
Form Electronic book
Author Nijkamp, Franciscus Petrus, 1947-
Parnham, Michael J., 1951-
LC no. 2005048217
ISBN 3764358041 (Paper)
376437408X
9783764358044 (Paper)
9783764374082