Description |
1 online resource (xvii, 602, [2] pages of plates) : illustrations (some color) |
Contents |
880-01 Ch. 1. Overview of protein conjugation -- ch. 2. Review of protein and nucleic acid chemistry -- ch. 3. Reagents targeted to specific functional groups -- ch. 4. How to design and choose cross-linking reagents -- ch. 5. Homobifunctional cross-linking reagents -- ch. 6. Heterobifunctional cross-linkers -- ch. 7. Multifunctional cross-linking reagents -- ch. 8. Monofunctional and zero-length cross-linking reagents -- ch. 9. General approaches for chemical cross-linking -- ch. 10. Analysis of cross-linked products -- ch. 11. Applications of chemical cross-linking to the study of biological macromolecules -- ch. 12. Applications of chemical conjugation in the preparation of immunoconjugates and immunogens -- ch. 13. Application of chemical conjugation for the preparation of immunotoxins and other drug conjugates for targeting theraputics -- ch. 14. Application of chemical conjugation to solid-state chemistry |
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880-01/(N Front Cover -- Contents -- Preface -- Authors -- Chapter 1: Overview of Protein Conjugation -- Chapter 2: Review of Protein and Nucleic Acid Chemistry -- Chapter 3: Reagents Targeted to Specific Functional Groups -- Chapter 4: How to Design and Choose Cross-Linking Reagents -- Homobifunctional Cross-Linking Reagents -- Chapter 6: Heterobifunctional Cross-Linkers -- Chapter 7: Multifunctional Cross-Linking Reagents -- Chapter 8: Monofunctional and Zero -Length Cross -Linking Reagents -- Chapter 9: General Approaches for Chemical Cross-Linking -- Chapter 10: Analysis of Cross-Linked Products -- Chapter 11: Applications of Chemical Cross-Linking to the Study of Biological Macromolecules -- Chapter 12: Applications of Chemical Conjugation in the Preparation of Immunoconjugates and Immunogens -- Chapter 13: Application of Chemical Conjugation for the Preparation of Immunotoxins and Other Drug Conjugates for Targeting Therapeutics -- Chapter 14: Application of Chemical Conjugation to Solid-State Chemistry -- Appendix Ађ́ёAmino Group-Directed Homobifunctional Cross-Linkers -- Appendix Вђ́ёSulfhydryl Group-Directed Homobifunctional Cross-Linkers -- Appendix Сђ́ёPhenolate- and Imidazolyl-Group-Directed Reagents: Bisdiazonium Precursors -- Appendix Dђ́ёGroup Selective Heterobifunctional Cross-Linkers -- Appendix Еђ́ёPhotoactivatable Heterobifunctional Cross-Linking Reagents -- Back Cover |
Summary |
Since the publication of the first edition of Chemistry of Protein Conjugation and Cross-Linking in 1991, new cross-linking reagents, notably multifunctional cross-linkers, have been developed and synthesized. The completion of the human genome project has opened a new area for studying nucleic acid and protein interactions using nucleic acid cross-linking reagents, and advances have also been made in the area of biosensors and microarray biochips for the detection and analysis of genes, proteins, and carbohydrates. In addition, developments in physical techniques with unprecedented sensitivit |
Notes |
Revised edition of: Chemistry of protein conjugation and cross-linking. c1991 |
Bibliography |
Includes bibliographical references and index |
Subject |
Proteins -- Crosslinking.
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Proteins -- chemistry
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Cross-Linking Reagents
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Immunoconjugates -- chemistry
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Immunoconjugates -- therapeutic use
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Nucleic Acids -- chemistry
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Proteins -- Crosslinking.
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Konjugiertes System
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Nucleinsäuren
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Proteine
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Form |
Electronic book
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Author |
Jameson, David M
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Wong, Shan S.
Chemistry of protein conjugation and cross-linking
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ISBN |
9781420007640 |
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1420007645 |
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084937491X |
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9780849374913 |
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