Description |
1 online resource |
Series |
Advances in experimental medicine and biology ; v. 738 |
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Advances in experimental medicine and biology ; v. 738. 0065-2598
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Contents |
The origin of the bacterial immune response / Jesús Martínez Borra, Segundo González, and Carlos López Larrea -- The evolution of self during the transition to multicellularity / Aurora M. Nedelcu -- Glyconectin glycans as the self assembling nano molecular velcrosystem mediating self nonself recognition and adhesion implicated in evolution of multicellularity / Gradimir N. Misevic, Nikola Misevic, and Octavian Popescu -- Neglected biological features in cnidarians self nonself recognition / Baruch Rinkevich -- Intracellular inflammatory sensors for foreign invaders and substances of self origin / Nao Jounai, Kouji Kobiyama, and Fumihiko Takeshita -- Nonself perception in plant innate immunity / Ian A. Dubery, Natasha M. Sanabria, and Ju Chi Huang -- How did flowering plants learn to avoid blind date mistakes self incompatibility in plants and comparisons with nonself rejection in the immune response / Philip J. Kear and Bruce McClure -- Signaling pathways that regulate life and cell death : evolution of apoptosis in the context of self defense / Cristina Muñoz Pinedo -- Sensing necrotic cells / Yasunobu Miyake and Sho Yamasaki |
Summary |
In 1960 Sir Frank Macfarlane Burnet received the Noble Prize in Physiology and Medicine. He titled his Nobel Lecture "Immunological Recognition of Self" emphasizing the central argument of immunological tolerance in "How does the vertebrate organism recognize self from nonself in this the immunological sense-and how did the capacity evolve." The concept of self is linked to the concept of biological self identity. All organisms, from bacteria to higher animals, possess recognition systems to defend themselves from nonself. Even in the context of the limited number of metazoan phyla that have been studied in detail, we can now describe many of the alternative mechanism of immune recognition that have emerged at varying points in phylogeny. Two different arms-the innate and adaptive immune system-have emerged at different moments in evolution, and they are conceptually different. The ultimate goals of immune biology include reconstructing the molecular networks underlying immune processes |
Analysis |
biomedische wetenschappen |
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biomedicine |
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immunologie |
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immunology |
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Medicine (General) |
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Geneeskunde (algemeen) |
Bibliography |
Includes bibliographical references and index |
Notes |
Print version record |
Subject |
Natural immunity.
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Cellular recognition.
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Immunologic memory.
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Self Tolerance -- immunology
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Adaptive Immunity
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Immunity, Innate
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Immunologic Memory
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MEDICAL -- Immunology.
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Cellular recognition
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Immunologic memory
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Natural immunity
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Form |
Electronic book
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Author |
López-Larrea, Carlos, 1953-
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ISBN |
9781461416807 |
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1461416809 |
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