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E-book
Author Mughal, Tariq I.

Title Chronic myeloid leukemia : a handbook for oncologists and hematologists / Tariq I. Mughal
Published Boca Raton, FL : CRC Press, [2013]
©2013
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Description 1 online resource : illustrations
Contents 1. An introduction to chronic myeloid leukemia -- 2. A historical perspective of chronic myeloid leukemia -- 3. Cytogenetics, molecular anatomy, and molecular biology of chronic myeloid leukemia -- 4. Clinical aspects, prognostic and predictive factors -- 5. Primary treatment of chronic myeloid leukemia -- 6. Secondary treatment and stem cell transplantation for chronic myeloid leukemia -- 7. Emerging and investigational treatment for chronic myeloid leukemia -- 8. Defi nitions of response and monitoring response for patients with chronic myeloid leukemia -- 9. Resistance to tyrosine kinase inhibitors and novel insights into genomic instability of chronic myeloid leukemia stem cells -- 10. Concluding thoughts
Summary Chronic myeloid leukemia is a clonal disease that results from an acquired genetic change in a single pluripotential hemopoietic stem cell. Efforts to confront this disease have been assisted by advances in cellular and molecular biology and the speed at which these findings have transformed the therapeutic algorithm. Nevertheless, there is some uncertainty with regards to how best to assess efficacy of treatment, especially with regards to the most appropriate surrogate markers for overall survival. From the standpoint of biology and clinical management, this handbook provides an authoritativ
Bibliography Includes bibliographical references
Notes Print version record
Subject Leukemia -- Handbooks, manuals, etc.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive.
Genre/Form Handbook.
Handbooks and manuals.
Handbooks and manuals.
Form Electronic book
ISBN 1842145789 (electronic bk.)
9781842145784 (electronic bk.)