| Description |
1 online resource (236 pages) |
| Contents |
Cover; Half-title; Title; Copyright; Dedication; Contents; Contributors; Foreword; Preface; 1 The cannabinoid system: from the point of view of a chemist; Cannabis and mental illness; Understanding cannabinoid chemistry; Cannabidiol; The endocannabinoids; Anandamide; Arachidonoylglycerol (2-AG); Additional endocannabinoids; Biosynthesis and inactivation of the endocannabinoids; Synthetic cannabinoids; Quo vadimus?; REFERENCES; 2 How cannabis works in the brain; Cannabinoid receptors; Neuroanatomical distribution of CB1 receptors in brain; Effects of cannabinoids on synaptic function |
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Inhibition of neurotransmitter releaseEndogenous cannabinoids act as retrograde signal molecules at synapses; Effects of cannabinoids on CNS function and psychomotor control; Cannabinoid mechanisms in the hippocampus and effects on memory; Cannabinoids and the neocortex; Effects of cannabinoids on hypothalamic control of appetite; Cannabis as an intoxicant and drug of dependence; Cannabis intoxication; Tolerance and dependence; Conclusions; REFERENCES; 3 Acute and subacute psychomimetic effects of cannabis in humans; Historical accounts; Surveys of cannabis users |
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Human experiments on psychomimetic effects of cannabisEuphoria and laughter; Anxiety symptoms with cannabis intoxication; Immediate effects on cognition and psychomotor functioning; The 'amotivational' syndrome; Conclusions; REFERENCES; 4 The association between cannabis use and depression: a review of the evidence; Introduction; Comorbidity between cannabis use and depression; Clinical samples; Convenience samples; Representative samples of the general population; Summary; What explains the association between cannabis use and depression?; Cannabis use causes depression |
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Depression causes cannabis useCommon factors increase the risk of both depression and cannabis use; A review of relevant evidence; Studies of the effects of cannabis use upon mood; Cross-sectional surveys of the general population; The use of longitudinal research to examine questions about causality; Does cannabis use predict later depression?; Does depression predict later cannabis use?; Summary; Implications for future research; Measurement of cannabis use; Measurement of depression; Study designs; Longitudinal studies; The use of genetically informative designs to examine causality |
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ConclusionsREFERENCES; 5 Cannabis and psychosis proneness; Psychosis proneness in cannabis users; Is there a cross-sectional association between cannabis use and psychosis proneness?; Methodological considerations; Implications; Does cannabis induce the occurrence of psychotic experiences in non-clinical subjects?; Is the risk of acute psychotic experiences induced by cannabis increased in subjects with a pre-existing psychosis vulnerability?; Is there an interaction between cannabis use and psychosis vulnerability in their effects on psychotic experiences in daily life? |
| Summary |
This book provides a comprehensive overview of the psychiatry and neuroscience of Cannabis sativa (marijuana), with particular emphasis on psychotic disorders. It outlines developments in our understanding of the human cannabinoid system, and links this knowledge to clinical and epidemiological facts about the impact of cannabis on mental health. Clinically focused chapters review not only the direct psychomimetic properties of cannabis, but also the impact consumption has on the courses of evolving or established mental illness such as schizophrenia. A number of controversial issues are crit |
| Notes |
Is there an interaction between cannabis use and psychosis vulnerability in their effects on increased incidence of psychotic disorder? |
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Print version record |
| Subject |
Marijuana -- Physiological effect
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Marijuana -- Psychological aspects
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Marijuana abuse -- Complications
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Psychoses -- Etiology
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Schizophrenia -- Etiology
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Marijuana -- Physiological effect
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Marijuana -- Psychological aspects
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Psychoses -- Etiology
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Schizophrenia -- Etiology
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| Form |
Electronic book
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| Author |
Murray, Robin
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| ISBN |
9780511194412 |
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0511194412 |
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