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Title Mitochondrial dysfunction in neurodegenerative disorders / Amy Katherine Reeve [and others], editors
Published London : Springer, [2012]
Online access available from:
Springer eBooks    View Resource Record  


Description 1 online resource (xxi, 242 pages) : illustrations
Contents pt. 1. Mitochondrial function and genetics -- pt. 2. Mitochondrial dysfunction : causes and effects? -- pt. 3. Functional consequences of mitochondrial dysfunction -- pt. 4. Modeling mitochondrial contribution to neurodegerative diseases -- pt. 5. The future
Summary As age related diseases increase in prevalence and impact more significantly on medical resources it is imperative to understand these diseases and the mechanisms behind their progression. New research has stimulated a growing interest in mitochondrial involvement in neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease and multiple sclerosis and the mechanisms which lead from mitochondrial dysfunction to neurodegeneration. ¡ Mitochondrial Dysfunction in Neurodegenerative Disorders brings together contributions from leaders in the field internationally on the various ways in which mitochondrial dysfunction contributes to the pathogenesis of these diseases, guiding the reader through the basic functions of mitochondria and the mechanisms that lead to their dysfunction, to the consequences of this dysfunction on neuronal function before finishing with the modelling of these disorders and discussion of new potential therapeutic targets. ¡ Mitochondrial Dysfunction in Neurodegenerative Disorders provides an accessible, authoritative guide to this important area for neurologists; research and clinical neuroscientists; neuropathologists; and residents with an interest in clinical research
Analysis Medicine
Bibliography Includes bibliographical references and index
Subject Nervous system -- Degeneration.
Mitochondrial pathology.
Mitochondria -- pathology.
Mitochondria -- metabolism.
Mitochondrial Diseases -- pathology.
Nerve Degeneration.
Neurodegenerative Diseases -- pathology.
Form Electronic book
Author Reeve, Amy Katherine.
LC no. 2011941274
ISBN 9780857297013 (electronic bk.)
0857297015 (electronic bk.)