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Mitochondrial Membranes -- metabolism. : Initiation and elongation of mammalian mitochondrial protein synthesis / Linda L. Spremulli  2018 1
 

Mitochondrial Membranes, Outer -- See Mitochondrial Membranes


The two lipoprotein layers in the MITOCHONDRION. The outer membrane encloses the entire mitochondrion and contains channels with TRANSPORT PROTEINS to move molecules and ions in and out of the organelle. The inner membrane folds into cristae and contains many ENZYMES important to cell METABOLISM and energy production (MITOCHONDRIAL ATP SYNTHASE)
  1
 

Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes -- See MELAS Syndrome


A mitochondrial disorder characterized by focal or generalized seizures, episodes of transient or persistent neurologic dysfunction resembling strokes, and ragged-red fibers on muscle biopsy. Affected individuals tend to be normal at birth through early childhood, then experience growth failure, episodic vomiting, and recurrent cerebral insults resulting in visual loss and hemiparesis. The cortical lesions tend to occur in the parietal and occipital lobes and are not associated with vascular occlusion. VASCULAR HEADACHE is frequently associated and the disorder tends to be familial. (From Joynt, Clinical Neurology, 1992, Ch56, p117)
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Mitochondrial Myopathy, Lactic Acidosis, Stroke-Like Episode -- See MELAS Syndrome


A mitochondrial disorder characterized by focal or generalized seizures, episodes of transient or persistent neurologic dysfunction resembling strokes, and ragged-red fibers on muscle biopsy. Affected individuals tend to be normal at birth through early childhood, then experience growth failure, episodic vomiting, and recurrent cerebral insults resulting in visual loss and hemiparesis. The cortical lesions tend to occur in the parietal and occipital lobes and are not associated with vascular occlusion. VASCULAR HEADACHE is frequently associated and the disorder tends to be familial. (From Joynt, Clinical Neurology, 1992, Ch56, p117)
  1
 

Mitochondrial pathology -- See Also the narrower term Mitochondrial DNA Abnormalities


  1
Mitochondrial pathology.   41
Mitochondrial pathology -- Case studies. : Mitochondrial case studies : underlying mechanisms and diagnosis / edited by Russell P. Saneto, Department of Neurology/Division of Pediatric Neurology, Seattle Children's Hospital/University of Washington, Seattle, WA, USA, Sumit Parikh, Cleveland Clinic Lerner College of Medicine & Case Western Reserve University, Cleveland, OH, USA ; Neurogenetics, Metabolism and Mitochondrial Disease Center, Cleveland Clinic, Cleveland, OH, USA, Bruce H. Cohen, Northeast Ohio Medical University, Rootstown, OH, USA ; The NeuroDevelopmental Science Center and Division of Neurology, Department of Pediatrics, Children's Hospital and Medical Center of Akron, Akron, OH, USA  2016 1
Mitochondrial pathology -- Diagnosis -- Case studies. : Mitochondrial case studies : underlying mechanisms and diagnosis / edited by Russell P. Saneto, Department of Neurology/Division of Pediatric Neurology, Seattle Children's Hospital/University of Washington, Seattle, WA, USA, Sumit Parikh, Cleveland Clinic Lerner College of Medicine & Case Western Reserve University, Cleveland, OH, USA ; Neurogenetics, Metabolism and Mitochondrial Disease Center, Cleveland Clinic, Cleveland, OH, USA, Bruce H. Cohen, Northeast Ohio Medical University, Rootstown, OH, USA ; The NeuroDevelopmental Science Center and Division of Neurology, Department of Pediatrics, Children's Hospital and Medical Center of Akron, Akron, OH, USA  2016 1
Mitochondrial pathology -- Handbooks, manuals, etc : Handbook of mitochondrial dysfunction / edited by Shamim I. Ahmad  2019 1
mitochondrial permeability transition pore : Mitochondria and calcium signaling in cell life and cell death / Michael R. Duchen  2018 1
 

Mitochondrial Protein -- See Mitochondrial Proteins


Proteins encoded by the mitochondrial genome or proteins encoded by the nuclear genome that are imported to and resident in the MITOCHONDRIA
  1
Mitochondrial Proteins.   6
Mitochondrial Proteins -- biosynthesis. : Initiation and elongation of mammalian mitochondrial protein synthesis / Linda L. Spremulli  2018 1
Mitochondrial Proteins -- chemistry.   2
Mitochondrial Proteins -- metabolism.   6
 

Mitochondrial Respiratory Chain Deficiencies -- See Mitochondrial Diseases


Diseases caused by abnormal function of the MITOCHONDRIA. They may be caused by mutations, acquired or inherited, in mitochondrial DNA or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondria dysfunction due to adverse effects of drugs, infections, or other environmental causes
  1
 

Mitochondrion -- See Mitochondria


Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)
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Mitochondrion, Heart -- See Mitochondria, Heart


The mitochondria of the myocardium
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Mitochondrion, Muscle -- See Mitochondria, Muscle


Mitochondria of skeletal and smooth muscle. It does not include myocardial mitochondria for which MITOCHONDRIA, HEART is available
  1
Mitogen-Activated Protein Kinase 1 -- metabolism. : The ERK1/2 MAPK cascade / Melanie H. Cobb  2014 1
Mitogen-Activated Protein Kinase 3 -- metabolism. : The ERK1/2 MAPK cascade / Melanie H. Cobb  2014 1
 

Mitogen-Activated Protein Kinase Kinases -- See Also MAP Kinase Signaling System


An intracellular signaling system involving the MAP kinase cascades (three-membered protein kinase cascades). Various upstream activators, which act in response to extracellular stimuli, trigger the cascades by activating the first member of a cascade, MAP KINASE KINASE KINASES; (MAPKKKs). Activated MAPKKKs phosphorylate MITOGEN-ACTIVATED PROTEIN KINASE KINASES which in turn phosphorylate the MITOGEN-ACTIVATED PROTEIN KINASES; (MAPKs). The MAPKs then act on various downstream targets to affect gene expression. In mammals, there are several distinct MAP kinase pathways including the ERK (extracellular signal-regulated kinase) pathway, the SAPK/JNK (stress-activated protein kinase/c-jun kinase) pathway, and the p38 kinase pathway. There is some sharing of components among the pathways depending on which stimulus originates activation of the cascade
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Mitogen-Activated Protein Kinase Kinases -- metabolism. : Stress-activated protein kinases / Francesc Posas, Angel R. Nebreda, eds  2008 1
 

Mitogen-Activated Protein Kinases -- See Also MAP Kinase Signaling System


An intracellular signaling system involving the MAP kinase cascades (three-membered protein kinase cascades). Various upstream activators, which act in response to extracellular stimuli, trigger the cascades by activating the first member of a cascade, MAP KINASE KINASE KINASES; (MAPKKKs). Activated MAPKKKs phosphorylate MITOGEN-ACTIVATED PROTEIN KINASE KINASES which in turn phosphorylate the MITOGEN-ACTIVATED PROTEIN KINASES; (MAPKs). The MAPKs then act on various downstream targets to affect gene expression. In mammals, there are several distinct MAP kinase pathways including the ERK (extracellular signal-regulated kinase) pathway, the SAPK/JNK (stress-activated protein kinase/c-jun kinase) pathway, and the p38 kinase pathway. There is some sharing of components among the pathways depending on which stimulus originates activation of the cascade
  1
Mitogen-activated protein kinases.   4
Mitogen-Activated Protein Kinases -- metabolism.   3
 

Mitogens -- See Also the narrower term Fibroblast growth factors


  1
 

Mitogens, Endogenous -- See Growth Substances


Signal molecules that are involved in the control of cell growth and differentiation
  1
 

Mitophagy -- See Mitochondrial Degradation


Proteolytic breakdown of the MITOCHONDRIA
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Mitoses -- See Mitosis


A type of CELL NUCLEUS division by means of which the two daughter nuclei normally receive identical complements of the number of CHROMOSOMES of the somatic cells of the species
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Mitosis.   7
Mitosis -- drug effects. : Beyond apoptosis : cellular outcomes of cancer therapy / edited by Igor B. Roninson, J. Martin Brown, Dale E. Bredesen  2008 1
Mitosis -- Juvenile films. : Mitosis  2000 1
 

Mitosporic fungi -- See Fungi imperfecti


  1
Mitosporic Fungi -- pathogenicity. : Carpet monsters and killer spores : a natural history of toxic mold / Nicholas P. Money  2004 1
 

Mitotic cycle -- See Cell cycle


  1
 

Mitotic M Phase -- See Mitosis


A type of CELL NUCLEUS division by means of which the two daughter nuclei normally receive identical complements of the number of CHROMOSOMES of the somatic cells of the species
  1
 

Mitotic M Phases -- See Mitosis


A type of CELL NUCLEUS division by means of which the two daughter nuclei normally receive identical complements of the number of CHROMOSOMES of the somatic cells of the species
  1
 

Mitrailleuses -- See Machine guns


  1
  Mitral incompetence -- 2 Related Subjects   2
 

Mitral Insufficiency -- See Mitral Valve Insufficiency


Backflow of blood from the LEFT VENTRICLE into the LEFT ATRIUM due to imperfect closure of the MITRAL VALVE. This can lead to mitral valve regurgitation
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  Mitral regurgitation -- 2 Related Subjects   2
Mitral Valve.   3
 

Mitral valve Diseases -- See Also the narrower term Mitral valve insufficiency


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Mitral valve -- Diseases.   6
Mitral valve -- Diseases -- Imaging.   2
Mitral valve -- Displacement. : Mitral valve prolapse / Daniel Shindler  c2020 1
Mitral valve -- Imaging. : An atlas of mitral valve imaging / Milind Desai, Christine Jellis, Teerapat Yingchoncharoen, editors  2015 1
 

Mitral Valve Incompetence -- See Mitral Valve Insufficiency


Backflow of blood from the LEFT VENTRICLE into the LEFT ATRIUM due to imperfect closure of the MITRAL VALVE. This can lead to mitral valve regurgitation
  1
Mitral valve insufficiency.   7
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