| Description |
1 online resource (xv, 272 pages) : illustrations (some color) |
| Series |
Springer protocols |
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Methods in molecular biology, 1940-6029 ; 1383 |
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Springer protocols (Series)
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Methods in molecular biology (Clifton, N.J.) ; v. 1383
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| Contents |
Mass spectrometry in clinical laboratory : applications in therapeutic drug monitoring and toxicology / Uttam Garg and Yan Victoria Zhang -- Quantitation of flecainide, mexiletine, propafenone, and amiodarone in serum or plasma using liquid chromatography-tandem mass spectrometry (LC-MS/MS) / Matthew H. Slawson and Kamisha L. Johnson-Davis -- Quantitation of the oral anticoagulants dabigatran, rivaroxaban, apixaban, and warfarin in plasma using ultra-performance liquid chromatography with tandem mass spectrometry (UPLC-MS/MS) / Jaime H. Noguez and James C. Ritchie -- Simultaneous quantitation of lamotrigine, levetiracetam, 10-Hydroxycarbazepine, topiramate, and zonisamide in serum using HPLC-MS/MS / Dean C. Carlow, Heng Shi, and Ryan C. Schofield -- Quantification of the triazole antifungal compounds voriconazole and posaconazole in human serum or plasma using liquid chromatography electrospray tandem mass spectrometry (HPLC-ESI-MS/MS) / Alejandro R. Molinelli and Charles H. Rose IV -- Quantitation of haloperidol, fluphenazine, perphenazine, and thiothixene in serum or plasma using liquid chromatography-tandem mass spectrometry (LC-MS/MS) / Matthew H. Slawson and Kamisha L. Johnson-Davis -- Quantitation of total buprenorphine and norbuprenorphine in meconium by LC-MS/MS / Stephanie J. Marin and Gwendolyn A. McMillin -- Quantitation of buprenorphine, norbuprenorphine, buprenorphine glucuronide, norbuprenorphine glucuronide, and naloxone in urine by LC-MS/MS / Stephanie J. Marin and Gwendolyn A. McMillin -- Simple liquid chromatography tandem mass spectrometry method for quantitation of plasma busulfan / Shuang Deng [and others] -- High-throughput quantitation of busulfan in plasma using ultrafast solid-phase extraction tandem mass spectrometry (SPE-MS/MS) / Loralie J. Langman [and others] -- Quantification of 11-carboxy-delta-9-tetrahydrocannabinol (THC-COOH) in meconium using gas chromatography/mass spectrometry (GC/MS) / Judy Peat [and others] -- Quantitation of carisoprodol and meprobamate in urine and plasma using liquid chromatography-tandem mass spectrometry (LC-MS/MS) / Matthew H. Slawson and Kamisha L. Johnson-Davis -- Cetirizine quantification by high-performance liquid chromatography tandem mass spectrometry (LC-MS/MS) / Ada Munar [and others] -- Quantification of docetaxel in serum using turbulent flow liquid chromatography electrospray tandem mass spectrometry (TFC-HPLC-ESI-MS/MS) / Christopher A. Crutchfield, Mark A. Marzinke, and William A. Clarke -- Comprehensive urine drug screen by gas chromatography/mass spectrometry (GC/MS) / Bheemraj Ramoo [and others] -- Broad-spectrum drug screening using liquid chromatography-hybrid triple-quadrupole linear ion trap mass spectrometry / Judy Stone -- High-resolution mass spectrometry for untargeted drug screening / Alan H.B. Wu and Jennifer Colby -- Quantitation of ethyl glucuronide and ethyl sulfate in urine using liquid chromatography-tandem mass spectrometry (LC-MS/MS) / Matthew H. Slawson and Kamisha L. Johnson-Davis -- Quantification of hydroxychloroquine in blood using turbulent flow liquid chromatography-tandem mass spectrometry (TFLC-MS/MS) / Allison B. Chambliss, Anna K. Füzéry, and William A. Clarke -- Quantification of iohexol in serum by high-performance liquid chromatography-tandem mass spectrometry (LC- MS/MS) / Faye B. Vicente [and others] -- Quantitation of teriflunomide in human serum/plasma across a 40,000-fold concentration range by LC/MS/MS / Geoffrey S. Rule, Alan L. Rockwood, and Kamisha L. Johnson-Davis -- Determination of menthol in plasma and urine by gas chromatography/mass spectrometry (GC/MS) / Judy Peat [and others] -- Development of an assay for methotrexate and Its metabolites 7-hydroxy methotrexate and DAMPA in serum by LC-MS/MS / Ryan C. Schofield [and others] -- Quantitative, multidrug pain medication testing by liquid chromatography : tandem mass spectrometry (LC-MS/MS) / Geza S. Bodor -- Quantification of free phenytoin by liquid chromatography tandem mass spectrometry (LC/MS/MS) / Judy Peat, Clint Frazee, and Uttam Garg -- Detection of stimulants and narcotics by liquid chromatography-tandem mass spectrometry and gas chromatography-mass spectrometry for sports doping control / Brian D. Ahrens, Yulia Kucherova, and Anthony W. Butch -- Quantification of tricyclic antidepressants in serum using liquid chromatography electrospray tandem mass spectrometry (HPLC-ESI-MS/MS) / Christopher A. Crutchfield, Autumn R. Breaud, and William A. Clarke |
| Summary |
This volume describes methods and protocols for a number of drugs and toxins in a stepwise manner. Chapters in the book cover a wide array of topics such as: quantitation of Flecainide, Mexiletine, Propafenone, and Amiodarone in Serum or Plasma; quantitation of total Buprenorphine and Norbuprenorphine in Meconium; quantitation or Carisoprodol and Meprobamate in Urine; and quantitation of Tricyclic Antidepressants in Serum. Each chapter contains a brief introduction to the topic, clinical utility of the analyte(s), and useful notes to help laboratorians easily reproduce the protocols discussed. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Clinical Applications of Mass Spectrometry in Drug Analysis: Methods and Protocols, is a great resource for laboratorians who are already using mass spectrometry or thinking of introducing this technology to their laboratories |
| Bibliography |
Includes bibliographical references and index |
| Subject |
Mass spectrometry.
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Clinical chemistry.
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Pharmaceutical Preparations -- analysis
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Mass Spectrometry -- methods
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Chemistry, Clinical -- methods
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Molecular Diagnostic Techniques
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Mass Spectrometry
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Chemistry, Clinical
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mass spectrometry.
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Pharmacology.
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Medical -- Pharmacology.
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Clinical chemistry
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Mass spectrometry
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| Genre/Form |
Laboratory manuals
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Laboratory manuals.
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Manuels de laboratoire.
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| Form |
Electronic book
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| Author |
Garg, Uttam.
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| ISBN |
9781493932528 |
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1493932527 |
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1493932519 |
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9781493932511 |
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