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Title Molecular mimicry : infection inducing autoimmune disease / M.B.A. Oldstone (ed.)
Published Berlin ; New York : Springer, [2005]
©2005
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Description 1 online resource (166 pages) : illustrations
Series Current topics in microbiology and immunology, 0070-217X ; v. 296
Current topics in microbiology and immunology ; v. 296. 0070-217X
Contents Molecular mimicry, microbial infection, and autoimmune disease : evolution of the concept / M.B.A. Oldstone -- The structural interactions between T cell receptors and MHC-peptide complexes place physical limits on self-nonself discrimination / K.W. Wucherpfennig -- A virus-induced molecular mimicry model of multiple sclerosis / J.K. Olson, A.M. Ercolini, and S.D. Miller -- Suppression of autoimmunity via microbial mimics of altered peptide ligands / L. Steinman, P.J. Utz, and W.H. Robinson -- Molecular and cellular mechanisms, pathogenesis, and treatment of insulin-dependent diabetes obtained through study of a transgenic model of molecular mimicry / M.B.A. Oldstone -- Trypanosoma cruzi-induced molecular mimicry and Chagas' disease / N. Gironès, H. Cuervo, and M. Fresno -- HTLV-1 induced molecular mimicry in neurological disease / S.M. Lee [and others] -- Molecular mimicry : anti-DNA antibodies bind microbial and nonnucleic acid self-antigens / J.S. Rice [and others] -- Chlamydia and antigenic mimicry / K. Bachmaier and J.M. Penninger
Summary "Molecular mimicry as a pathogenic mechanism for understanding and developing insights into therapies for autoimmune disease was first presented in the early 1980s. By the end of the 1980s, sufficient reports occurred to publish a Current Topics in Microbiology and Immunology volume (vol. 145, 1989) focusing on the developing evidence for or against molecular mimicry as a cause of autoimmunity. In the ensuing years a plethora of reports using experimental models and studying human diseases have surfaced to firmly establish the concept and its potential role in several autoimmune disorders. This current volume selects several of these examples of molecular mimicry from recognized experts, who present their original findings. In addition, chapters on the evolution of the concept, its strengths and weaknesses are included in this volume."--Jacket
Bibliography Includes bibliographical references and index
Subject Allergy -- Immunological aspects.
Autoimmune diseases.
Mimicry (Chemistry)
Autoimmune Diseases -- ethnology.
Autoimmune Diseases -- immunology.
Autoimmunity.
Infection -- complications.
Molecular Mimicry -- immunology.
Form Electronic book
Author Oldstone, Michael B. A.
LC no. 2007299676
ISBN 3540255974 (alk. paper)
3540307915 (electronic bk.)
9783540255970 (alk. paper)
9783540307914 (electronic bk.)