Description |
1 online resource (xxvii, 510 pages) : illustrations (some color) |
Series |
Metal ions in life sciences ; v. 6 |
|
Metal ions in life sciences ; v. 6.
|
Contents |
Organometallic chemistry of B₁₂ coenzymes -- Cobalamin- and corrinoid-dependent enzymes -- Nickel-alkyl bond formation in the active site of methyl-coenzyme M reductase -- Nickel-carbon bonds in acetyl-coenzyme a synthases/carbon monoxide dehydrogenases -- Structure and function of [NiFe]-hydro-genases -- Carbon monoxide and cyanide ligands in the active site of [FeFe]-hydrogenases -- Carbon monoxide as intrinsic ligand to iron in the active site of [Fe]-hydrogenase -- Dual role of heme as cofactor and substrate in the biosynthesis of carbon monoxide -- Copper-carbon bonds in mechanistic and structural probing of proteins as well as in situations where copper is a catalytic or receptor site -- Interaction of cyanide with enzymes containing vanadium, manganese, non-heme iron, and zinc -- Reaction mechanism of the molybdenum hydroxylase xanthine oxidoreductase: evidence against the formation of intermediates having metal-carbon bonds |
Summary |
The occurrence of a wide variety of metal-carbon bonds in living organisms, ranging from bacteria to humans, is only recently recognized. Of course, the historical examples are the B12 coenzymes containing cobalt-carbon bonds, but now such bonds are also known for nickel, iron, copper, and other transition metal ions. There is no other comparable book; MILS-6, written by 17 experts, summarizes the most recent insights into this fascinating topic |
Bibliography |
Includes bibliographical references and indexes |
Notes |
English |
Subject |
Metalloenzymes.
|
|
Coenzymes.
|
|
Organometallic compounds
|
|
Vitamin B12.
|
|
Coenzymes -- chemistry [mesh]
|
|
Organometallic Compounds -- chemistry [mesh]
|
|
Coenzymes -- chemistry
|
|
Organometallic Compounds -- chemistry
|
|
Coenzymes
|
|
Organometallic Compounds
|
|
Vitamin B 12
|
|
Multienzyme Complexes -- chemistry [mesh]
|
|
Oxidoreductases -- chemistry [mesh]
|
|
Vitamin B 12 -- chemistry [mesh]
|
|
Multienzyme Complexes -- chemistry
|
|
Oxidoreductases -- chemistry
|
|
Vitamin B 12 -- chemistry
|
|
organometallic compound.
|
|
Coenzymes
|
|
Metalloenzymes
|
|
Organometallic compounds
|
|
Vitamin B12
|
|
Cofaktor
|
|
Enzym
|
|
Metallorganische Verbindungen
|
Form |
Electronic book
|
Author |
Sigel, Astrid
|
|
Sigel, Helmut
|
|
Sigel, Roland K. O
|
ISBN |
9781847559333 |
|
1847559336 |
|
9781847559159 |
|
1847559158 |
|
9783110442793 |
|
3110442795 |
|
9783110436587 |
|
3110436582 |
|