| Description |
xxiv, 336 pages : illustrations, some coloured ; 30 cm. |
| Contents |
1. Introduction -- 2. Literature review -- 3. Materials and methods -- 4. Preparation and characterization of SBS fibrous scaffolds -- 5. Endothelialization of SBS fibrous scaffolds -- 6. Conslusion and future work -- References -- Appendix |
| Summary |
"The ideal scaffolds for creating synthetic small diameter blood vessels have not yet been found. The limitations of implanting these scaffolds are thrombosis formation, intemal hyperplasia and aneurysmal dilation. Electrospinning technique fabricates polymer scaffolds with average fibre diameters ranging from 50 to 500 nm which is similar to those observed in extracellular matrix of native blood vessels. Therefore, it promotes the adhesion, proliferation and growth of cells. Herein, we classify the polymers deployed for the fabrication into synthetic polymers, natural polymers and hybrid polymers. Further, the mechanical properties and the biological activities of the electrospun small diameter blood vessels including antithrombogenic ability and cell response are discussed." -- Abstract, page v. |
| Notes |
Thesis (Ph. D.)--Swinburne University of Technology, 2017 |
| Bibliography |
Includes bibliographical references |
| Subject |
Biomedical engineering.
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Nanofibers -- therapeutic use
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Blood-vessels
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Nanocomposites (Materials)
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Biomedical materials.
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| Genre/Form |
Academic theses.
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