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Book Cover
E-book

Title Cancer gene profiling : methods and protocols / edited by Robert Grützmann and Christian Pilarsky
Edition 2nd ed
Published New York, N.Y. : Humana Press : Springer, ©2016

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Description 1 online resource (x, 256 pages) : illustrations (some color)
Series Springer protocols
Methods in molecular biology, 1940-6029 ; 1381
Springer protocols (Series)
Methods in molecular biology (Clifton, N.J.) ; v. 1381
Contents Factors affecting the use of human tissues in biomedical research : implications in the design and operation of a biorepository / Daniel S. Atherton [and others] -- Tissue microdissection / Anja Rabien and Glen Kristiansen -- Tissue microarrays / Ana-Maria Dancau [and others] -- Gene expression analysis in the age of mass sequencing : an introduction / Christian Pilarsky, Lahiri Kanth Nanduri, and Janine Roy -- Quantitative DNA methylation profiling in cancer / Ole Ammerpohl [and others] -- Single-nucleotide polymorphism to associate cancer risk / Victoria Shaw, Katie Bullock, and William Greenhalf -- Exosomes in cancer disease / Margot Zöller -- MicroRNA (miRNA) profiling / Lu Gao and Feng Jiang -- Cancer gene profiling for response prediction / B. Michael Ghadimi and Peter Jo -- Target gene discovery for novel therapeutic agents in cancer treatment / Sanjay Tiwari, Ole Ammerpohl, and Holger Kalthoff -- Application of proteomics in cancer biomarker discovery : GeLC-MS/MS / Pedro R. Cutillas and Tatjana Crnogorac-Jurcevic -- Meta-analysis of cancer gene profiling data / Janine Roy, Christof Winter, and Michael Schroeder -- Reproducible, scalable fusion gene detection from RNA-Seq / Vladan Arsenijevic and Brandi N. Davis-Dusenbery -- Transcriptome sequencing for the detection of chimeric transcripts / Hsueh-Ting Chu
Summary This second edition volume brings together the experiences of leading scientists in the discipline of cancer gene profiling. Because cancer genes can be profiled in many different ways, Cancer Gene Profiling: Methods and Protocols, Second Edition explores different techniques and approaches needed to understand the key stages of cancer development, as using only one technique would be insufficient. This book provides readers with an overview of the state-of-the-art methods that will enable them to perform these experiments, and demonstrates the kind of analysis that is possible in our current biomedical research. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Cancer Gene Profiling: Methods and Protocols, Second Edition is a great resource for any student or practitioner with an interest in cancer gene profiling, and can be used in any well-equipped research laboratory
Bibliography Includes bibliographical references and index
Subject Cancer genes.
DNA microarrays.
Neoplasms -- genetics
Gene Expression Profiling -- methods
Microarray Analysis -- methods
Genes, Neoplasm
Medical genetics.
Oncology.
Medical -- Genetics.
Medical -- Oncology.
Cancer genes
DNA microarrays
Genre/Form Laboratory manuals.
Manuels de laboratoire.
Form Electronic book
Author Grützmann, Robert
Pilarsky, Christian
LC no. 2015958099
ISBN 9781493932047
1493932047