| Description |
1 online resource (1 volume) |
| Series |
Medical intelligence unit |
|
Medical intelligence unit (Unnumbered : 2003)
|
| Contents |
DNA methylation : three decades in search of function / Aharon Razin -- Epigenetic mechanisms of gene regulation : relationships between DNA methylation, histone modification, and chromatin structure / Keith D. Robertson -- DNA hypo- vs. hypermethylation in cancer : tumor specificity, tumor progression, and therapeutic implications / Melanie Ehrlich and Guanchao Jiang -- DNA methylation in urological cancers / Wolfgang A. Schulz and Hans-Helge Seifert -- DNA methylation in colorectal cancer / Jeremy R. Jass [and others] -- CpG island hypermethylation of tumor suppressor genes in human cancer : concepts, methodologies and uses / Michel Herranz and Manel Esteller -- The loss of methyl groups in DNA of tumor cells and tissues : the immunochemical approach / Alain Niveleau [and others] -- Identifying clinicopathological association of DNA hypermethylation in cancers using CpG island microarrays / Susan H. Wei [and others] -- Methylation analysis in cancer : (epi)genomic fast track from discovery to clinical routine / Carolina Haefliger, Sabine Maier and Alexander Olek |
|
Regulation of DNA methyltransferases in cancer / Nancy Detich and Moshe Szyf -- Inhibition of poly(ADP-ribosyl)ation allows DNA hypermethylation / Anna Reale [and others] -- The role of active demethylation in cancer and its therapeutic potential / Moshe Szyf [and others] -- Purine analogues and their role in methylation and cancer chemotherapy / Katherine L. Seley and Sylvester L. Mosley -- DNA methyltransferase inhibitors : paving the way for epigenetic cancer therapeutics / Gregory K. Reid and A. Robert MacLeod -- Preclinical and clinical studies on 5-aza-2'-deoxycytidine, a potent inhibitor of DNA methylation, in cancer therapy / Richard L. Momparler -- Anticancer gene therapy by in vivo DNA electrotransfer of MBD2 antisense / Pascal Bigey and Daniel Scherman |
| Summary |
Provides a comprehensive analysis of implications of DNA methylation on cancer diagnosis and cancer therapy. This volume focuses on cancer therapy by dissecting the basic principles of DNA methylation in cancer from molecular mechanisms to clinical trials. It is useful for oncologists, researchers, clinicians, and graduate students |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| In |
Springer e-books |
| Subject |
DNA -- Methylation
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Cancer -- Treatment.
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Cancer -- Molecular aspects.
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Neoplasms -- genetics
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DNA Methylation
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Neoplasms -- therapy
|
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MEDICAL -- Oncology.
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HEALTH & FITNESS -- Diseases -- Cancer.
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Neoplasms -- genetics.
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DNA Methylation.
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Neoplasms -- therapy.
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DNA -- Methylation.
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Cancer -- Molecular aspects.
|
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Biomédecine.
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Sciences de la vie.
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Cancer -- Molecular aspects
|
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Cancer -- Treatment
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DNA -- Methylation
|
| Form |
Electronic book
|
| Author |
Szyf, Moshe
|
| ISBN |
1417574585 |
|
9781417574582 |
|
9780387274430 |
|
038727443X |
|
030647848X |
|
9780306478482 |
|
