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E-book

Title Epigenetic regulation in the nervous system : basic mechanisms and clinical impact / edited by J. David Sweatt [and others]
Published San Diego : Elsevier Science, 2013

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Description 1 online resource (374 pages)
Contents An overview of the molecular basis for epigenetics / J. David Sweatt [and others] -- Histone modifications in the nervous system and neuropsychiatric disorders / Morgan Bridi, Ted Abel -- Active DNA demethylation and 5-hydroxymethylcytosine / Junjie U. Guo, Guo-li Ming, Hongjun Song -- The epigenetics of parental effects / Tie Yuan Zhang [and others] -- Epigenetic mechanisms in learning and memory / Jeremy J. Day, J. David Sweatt -- Drug addiction and reward / Alfred J. Robinson, Jian Feng, Eric J. Nestler -- The mind and it's nucleosomes: chromatin (dys)regulation in major psychiatric diseases / Rahul Bharadwaj, Cyril J. Peter, Schahram Akbarian -- HDAC inhibitors as novel therapeutics in aging and Alzheimer's disease / Alexi Nott [and others] -- miRNAs and neurodevelopmental disorders / Quan LIn, Yi E. Sun -- Imprinting the CNS and neurodevelopment disorders / Weston T. Powell, Janine M. LaSalle -- Neuronal genomic and epigenetic diversity / Michael J. McConnell, Fred H. Gage -- Adult neurogenesis / Jenny Hsieh, Hongjun Song -- Trangenerational inheritance in mammals / Isabelle M. Mansuy, Rahia Mashoodh, Frances A. Champagne -- Epigenetics: defining the frontiers of genomic function / Michael J. Meaney [and others]
Summary Behavioral Epigenetics is the study of how environmental factors affect alterations in behavior, addressing the fundamental mechanisms that shape development and individual vulnerability/resilience to adverse behavioral outcome. With an understanding of the molecular mechanisms involved in epigenetic modulation, researchers believe it will be possible to develop targeted therapies for those individuals in whom it malfunctions. This volume will address current understanding of the roles of epigenetic processes at the molecular/cellular level, their impact on neural development and behavior
Notes Includes index
Print version record
Subject Neurogenetics.
Neurologic manifestations of general diseases.
Nervous System Diseases -- genetics
Epigenomics -- methods
Neurologic Manifestations
HEALTH & FITNESS -- Diseases -- Nervous System (incl. Brain)
MEDICAL -- Neurology.
Neurologic manifestations of general diseases
Neurogenetics
Form Electronic book
Author Sweatt, J. David
ISBN 9780123944054
0123944058
9781283923903
1283923904