| Description |
1 online resource (394 pages) |
| Contents |
Front Cover; Contents; Preface to the Series-Historical and Conceptual Perspective of the Autonomic Nervous System Book Series; Preface; Contributors; 1 Sympathetic Innervation of the Immune System and its Role in Modulation of Immune Responses, Immune-Related Diseases Models, and Integrative Medicine; INTRODUCTION TO NEURAL MODULATION OF IMMUNE RESPONSES; IDENTIFICATION OF ADRENOCEPTORS ON CELLS OF THE IMMUNE SYSTEM; AUTONOMIC INNERVATION OF ORGANS OF THE IMMUNE SYSTEM; SYMPATHETIC NERVES MODULATE INNATE AND ACQUIRED IMMUNE RESPONSES |
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SYMPATHETIC NERVES MODULATE IMMUNE REACTIVITY IN DISEASE MODELS, AND AFFECT THE OUTCOME OF DISEASEINFECTIOUS DISEASE AND WOUND HEALING; AUTOIMMUNE DISORDERS; Breast cancer models; IMMUNE SENESCENCE; CHRONIC STRESS, IMMUNE SENESCENCE, AND A PATTERN OF IMMUNE CHANGES; SYMPATHETIC NERVES AND CATECHOLAMINES IN COMPLEMENTARY AND INTEGRATIVE MEDICINE; REFERENCES; 2 Interactions between the Adrenergic and Immune Systems; INTRODUCTION; HOW DOES THE IMMUNE SYSTEM SIGNAL THE PVN?; NEUROANATOMICAL PATHWAYS AND CONNECTIONS OF THE NEUROIMMUNE REGULATORY SYSTEM |
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BIOCHEMICAL MEDIATORS OF THE ACTIONS OF IMMUNE STIMULI ON THE CENTRAL NERVOUS SYSTEMFUNCTIONAL CONSEQUENCES OF IMMUNE STIMULI ON THE NEUROIMMUNE REGULATORY SYSTEM; EFFECTS OF HPA-AXIS ACTIVATION ON IMMUNE FUNCTION; EFFECTS OF SYMPATHETIC NERVOUS SYSTEM ACTIVATION ON IMMUNE FUNCTION; ADRENERGIC REGULATION OF ADAPTIVE IMMUNITY; DOES IT REALLY WORK LIKE THAT?; WHEN DO THE ADRENAL GLAND AND SYMPATHETIC NERVOUS SYSTEM EXERT THEIR COUNTERREGULATORY EFFECTS?; SUMMARY AND CONSIDERATION OF A NEW MODEL; ACKNOWLEDGEMENTS; REFERENCES; 3 Enteric Neural Reflexes and Secretion |
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COMPONENTS OF ENTERIC MICROCIRCUITSSENSORY CELLS; Chemical stimuli; Mechanical stimuli; IPANs; INTERNEURONS; Submucosal interneurons; Myenteric inputs; SECRETOMOTOR NEURONS; INTEGRATIVE FUNCTION; SUBSTANCE P IN INTESTINAL REFLEXES; CGRP IN INTESTINAL REFLEXES; GLUTAMATE IN INTESTINAL REFLEXES; NUCLEOSIDES AND NUCLEOTIDES; Adenosine modulation of intestinal reflexes; NUCLEOTIDES; Nucleotides in intestinal reflexes; COORDINATION OF SECRETION AND MOTILITY; ENTEROCHROMAFFIN CELL MODEL-BON CELLS; SUMMARY; REFERENCES; 4 The Cholinergic Anti-Inflammatory Pathway; INTRODUCTION |
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SYSTEMIC INFLAMMATION AS A THERAPEUTIC TARGETMAMMALIAN EVOLUTION CONFERRED REDUNDANT STRATEGIES FOR SUPPRESSING SYSTEMIC, LETHAL INFLAMMATION BY DEACTIVATING MACROPHAGES; SENSING PERIPHERAL INFLAMMATION; IMMUNE TO BRAIN COMMUNICATION: HUMORAL SUBSTRATES; IMMUNE TO BRAIN COMMUNICATION: AFFERENT NEURAL SIGNALS; THE CHOLINERGIC ANTI-INFLAMMATORY PATHWAY; BRAIN TO IMMUNE COMMUNICATION: EFFERENT NEURAL SIGNALS; Intravenous CNI-1493 accumulates in brain; The protective effects of CNI-1493 are abolished by surgical or chemical vagotomy; CNI-1493 activates neural signalling in the intact vagus nerve |
| Summary |
While it may appear that the nervous and immune systems exist as two separate entities, groundbreaking observations have positively identified anatomic connections between elements of the nervous system and cells of adaptive immunity. Building on this research, Autonomic Neuroimmunology presents a scientific discussion of the current understanding of these vital neuroimmunological interactions and their implications for normal psychology and disease states. Contributors document the cell biological mechanisms for the neuropeptide activation of mast cells, and analyze how one or more adrenergen |
| Notes |
Vagus nerve stimulation protects against endotoxin-induced hypotension |
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Print version record |
| Subject |
Autonomic nervous system -- Immunology
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Neuroimmunology.
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Viscera -- Innervation.
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Neuroimmunomodulation
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Neuroimmunology
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Viscera -- Innervation
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| Form |
Electronic book
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| Author |
Blennerhassett, M
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Goetzl, E
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| ISBN |
9781134401079 |
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1134401078 |
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