A transferase that catalyzes the addition of aliphatic, aromatic, or heterocyclic FREE RADICALS as well as EPOXIDES and arene oxides to GLUTATHIONE. Addition takes place at the SULFUR. It also catalyzes the reduction of polyol nitrate by glutathione to polyol and nitrite
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P-glycoprotein. : An introduction to p-glycoprotein / M. Wahajuddin, PHD, FHEA, FRSB, FRSC, Principal Scientist, CSIR-Central Drug Research Institute, Lucknow (U.P.), India, Ravindra Varma Alluri, PHD, Associate Principal Scientist, Clinical Pharmacology and Safety Sciences, AstraZeneca R&D, Cambridge, UK, Rahul Dev Jayant, PHD, Assistant Professor, Texas Tech University Health Sciences Center, Texas, USA, editors
A subfamily of transmembrane proteins from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS that are closely related in sequence to ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B, MEMBER 1. When overexpressed, they function as ATP-dependent efflux pumps able to extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing multidrug resistance (DRUG RESISTANCE, MULTIPLE). Although ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology
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p-Gruppe : Fusion systems in algebra and topology / Michael Aschbacher, Radha Kessar, Bob Oliver
P.M. Dawn (Musical group) / http://id.loc.gov/authorities/names/n92041894 : Contemporary Black biography. Volume 54 : profiles from the international Black community / Sara and Tom Pendergast, editors