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Title Innovation of diagnosis and treatment for pancreatic cancer / Hiroki Yamaue, editor
Published Singapore : Springer, 2017
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Description 1 online resource (vi, 260 pages) : illustrations (some color)
Contents Part I: Diagnosis of Pancreatic Cancer; 1: Early Diagnosis of Pancreatic Cancer Using Endoscopic Ultrasound; 1.1 Introduction; 1.2 EUS (Fig. 1.1); 1.3 Early Diagnosis of PC Using EUS; 1.4 Pancreatic Intraepithelial Neoplasia (PanIN); 1.5 Surveillance of High-Risk Individuals; 1.6 New Screening Modality Comprising Contrast EUS and Elastography; 1.7 Early Diagnosis of PC Using EUS-FNA (Fig. 1.3); References; 2: Evaluation of Resectability for Pancreatic Cancer Using Endoscopic Ultrasound; 2.1 Introduction; 2.2 EUS Diagnosis of Vascular Invasion in Pancreatic Cancer
2.3 EUS Diagnosis of Node Metastasis in Pancreatic Cancer2.4 EUS Diagnosis of Liver Metastases in Pancreatic Cancer; References; 3: Evaluation of Resectability of Pancreatic Cancer by MDCT; 3.1 Introduction; 3.2 Method of Contrast-Enhanced Dynamic MDCT for Pancreas; 3.3 Diagnosis of Extent of Spread of Pancreatic Cancer; 3.4 Final Remarks; References; 4: Evaluation of Effect of Neoadjuvant Therapy Using Positron Emission Tomography; 4.1 Introduction; 4.2 PET-CT: Diagnostic Efficacy in the Detection and Differential Diagnosis of Pancreatic Cancer; 4.2.1 Diagnostic Efficacy
4.2.2 Usefulness of PET for Selecting Initial Treatment4.3 Determining Prognosis According to PET-CT Parameters and Assessment of Metabolic Response by Neoadjuvant Treatment; 4.3.1 The Clinical Implications of SUV Values; 4.3.2 SUV Value After Neoadjuvant Therapy; 4.3.3 Volumetric and Other Parameters (GTV, MTV, TLG); 4.4 Current Research Gaps and Possible Future Work; References; 5: Liquid Biopsy for Early Detection of Pancreatic Cancer; 5.1 Implications of Early Diagnosis in Pancreatic Cancer; 5.2 Liquid Biopsy in Cancer; 5.2.1 Cell-Free DNA; 5.2.2 Origin of cfDNA
5.2.3 cfDNA as a Biomarker for Cancer5.2.4 Methods for Detection of ctDNA; 5.3 Liquid Biopsy in Pancreatic Cancer Diagnosis; 5.4 Challenges Facing Early Detection of Pancreatic Cancer by Liquid Biopsy; 5.5 Conclusions and Future Directions; References; Part II: Pancreaticoduodenectomy for Pancreatic Cancer: Indications and Procedure; 6: Standard Resection and Extended Resection; 6.1 Introduction; 6.2 Comparison Between Standard and Extended Resection; 6.2.1 Rationale for Dissection of Lymph Node and Nerve Plexus; 6.2.2 Extent of Pancreaticoduodenectomy
6.2.3 Results of Our Randomized Controlled Study6.2.4 Meta-Analyses on Optimal Extent of Resection; 6.3 Vascular Resection; References; 7: Pylorus-Resecting Pancreaticoduodenectomy; 7.1 Transition of Pancreaticoduodenectomy; 7.2 Procedure of PrPD; 7.3 Which Is Better, PD, PpPD, or PrPD?; 7.4 The Impact of Pylorus-Resecting Pancreaticoduodenectomy (PrPD); 7.5 Long-Term Outcomes in PrPD; References; 8: Pancreaticoduodenectomy with Portal Vein Resection; 8.1 Diagnostic Workup; 8.2 Classification of Venous Involvement; 8.3 Technical Aspects of Venous Resections
Summary This collection of chapters describes in detail the latest insights into the evaluation of resectability and neoadjuvant therapy to pancreaticoduodenectomy and distal pancreatectomy for pancreatic cancer. Shedding light on immunotherapy and gene therapy, this volume comprehensively covers treatments and procedures for the disease, allowing surgeons and trainees to gain an overview and explore innovative treatments. It also provides information on various cases using tools such as endoscopic ultrasound, MDCT, PET for diagnosis and laparoscopy and robotic resection methods. Edited and authored by pioneering professionals, Diagnosis and Treatment for Pancreatic Cancer is a valuable resource for gastroenterologists, medical oncologists, surgical oncologist and general surgeons interested in treatment of pancreatic cancer care
Notes Online resource; title from PDF title page (SpringerLink, viewed July 27, 2017)
Subject Pancreas -- Cancer -- Diagnosis -- Technological innovations.
Pancreas -- Cancer -- Treatment -- Technological innovations.
Pancreatic Neoplasms -- diagnosis.
Pancreatic Neoplasms -- therapy.
Form Electronic book
Author Yamaue, Hiroki, editor
ISBN 9789811024863 (electronic bk.)
9811024863 (electronic bk.)
(print)