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Title Cell signaling in vascular inflammation / edited by Jahar Bhattacharya
Published Totowa, N.J. : Humana Press, [2005]
Online access available from:
Springer eBooks    View Resource Record  


Description 1 online resource (xi, 221 pages) : illustrations
Contents Heme oxygenase-1 and carbon monoxide in vascular regulation / Stefan W. Ryter and Augustine M.K. Choi -- Tumor necrosis factor-[alpha]/receptor signaling through the Akt kinase / Osman Nidai Ozes [and others] -- Protein modifications by nitric oxide and reactive nitrogen species / Harry Ischiropoulos -- Redox signaling in hypoxic pulmonary vasoconstriction / E. Kenneth Weir [and others] -- cGMP-dependent protein kinase in regulation of the perinatal pulmonary circulation / Usha Raj [and others] -- Glutamate receptor activation in the pathogenesis of acute leg injury / Sami I. Said -- Carboxyl methylation of small GTPases and endothelial cell function / Sharon Rounds, Elizabeth O. Harrington, and Qing Lu -- Pressure-induced inflammatory signaling in lung endothelial cells / Wolfgang M. Kuebler -- Regulation of endothelial barrier function: contributions of the transcellular and paracellular pathways / Dolly Mehta, Richard D. Minshall, and Asrar B. Malik -- Sphingolipid signaling: implications for vascular biology / Margaret M. Harnett -- Regulations of cytokine signaling / Bao Q. Vuong [and others] -- Cell signaling by vasoactive agents / Barry L. Fanburg [and others] -- Reactive oxygen species and cell signaling in lung ischemia / Aron B. Fisher -- Pulmonary vascular barrier regulation by thrombin and Edg receptors / Jeffrey R. Jacobson and Joe G.N. Garcia -- Second-messenger signaling in lung capillaries / Kaushik Parthasarathi -- Plasma membrane-to-nucleus calcium signaling / Giles E. Hardingham -- Signaling by mitochondria / Navdeep S. Chandel -- Pro-inflammatory signaling by endothelial focal complexes in lung / Sunita Bhattacharya -- Hydrogen peroxide as intracellular messenger: production, target, and elimination / Sue Goo Rhee [and others] -- Calcium-inhibited adenylyl cyclase (AC₆) controls endothelial cell barrier function / Troy Stevens
Summary "In Cell Signaling in Vascular Inflammation, leading basic and clinical researchers review the signal transduction mechanisms responsible for lung inflammation, including vascular hyperpermeability, white cell accumulation, and vascular remodeling. The authors cut across disciplines to bring together a broad-based presentation of inflammatory challenge, both in the initial phases of the inflammatory response, as well as in the more prolonged phase of genomic involvement." "Authoritative and state-of-the-art, Cell Signaling in Vascular Inflammation offers physiologists, molecular and cell biologists, and pharmaceutical scientists a comprehensive survey of the signal transduction pathways in lung vascular cells that illuminates not only the processes of lung inflammation, but also the potential for developing new therapeutic strategies to combat inflammatory lung disease."--Jacket
Bibliography Includes bibliographical references and index
Subject Cellular signal transduction.
Inflammation -- Mediators.
Intercellular Signaling Peptides and Proteins.
Paracrine Communication -- physiology.
Vasculitis -- pathology.
Form Electronic book
Author Bhattacharya, Jahar.
ISBN 1280359161
1588295257 (alk. paper)
1592599095 (electronic bk.)
9781588295255 (alk. paper)
9781592599097 (electronic bk.)