| Description |
1 online resource (xi, 158 pages) : illustrations |
| Series |
Pharmacology - research, safety testing and regulation |
|
Pharmacology-research, safety testing, and regulation series.
|
| Contents |
PENICILLINBIOSYNTHESIS, APPLICATIONS AND ADVERSE EFFECTS; PHARMACOLOGY -- RESEARCH, SAFETY TESTING AND REGULATION; PENICILLINBIOSYNTHESIS, APPLICATIONS AND ADVERSE EFFECTS; LIBRARY OF CONGRESS CATALOGING-IN-PUBLICATION DATA; CONTENTS; PREFACE; CHAPTER 1. MOLECULAR MODIFICATION OF BIOSYNTHETIC GENES FOR IMPROVED PRODUCTION OF PENICILLINS AND CEPHALOSPORINS; ABSTRACT; INTRODUCTION; BIOSYNTHESIS OF b-LACTAM ANTIBIOTICS; Biosynthesis of Penicillin; Biosynthesis of Cephalosporin C; Biosynthesis of Cephamycin C; Biosynthesis of Cephabacin; DEVELOPMENT OF SEMI-SYNTHETIC PENICILLINS |
|
GENETIC MANIPULATION OF b-LACTAM PRODUCERS TO IMPROVE PENICILLIN PRODUCTION YIELDPenicillin Production Improved by Classical Strain-Improvement; Application of Molecular Biology Techniques for Improved Penicillin Production; DEVELOPMENT OF SEMI-SYNTHETIC CEPHALOSPORINS; INDUSTRIAL SYNTHESIS OF CEPHALOSPORIN PRECURSORS; GENETIC MANIPULATION OF (SB (B-LACTAM PRODUCERS TO IMPROVE CEPHALOSPORIN PRODUCTION; KEY ENZYMES IN b-LACTAM BIOSYNTHESIS; Isopenicillin N Synthase (IPNS); Deacetoxycephalosporin C Synthase (DAOCS); DAOCS: a Fe(II) and 2-Oxoglutarate Dependent Dioxygenase |
|
Biochemical Characterization of DAOCSStructural and Mechanistic Studies of DAOCS; Modification of DAOCS to Improve its Substrate Bindingand Catalytic Activity; Recombinant DAOCSs; Rational Engineering of DAOCS; FUTURE DEVELOPMENT OF b-LACTAM ANTIBIOTICS; REFERENCES; CHAPTER 2. DEVELOPMENTS IN THE SEPARATION AND RECOVERY OF PENICILLIN G USING HOLLOW-FIBER MEMBRANE CONTACTORS; ABSTRACT; NOTATION; Subscripts; Superscripts; Greek Symbols; INTRODUCTION; MECHANISM AND KINETICS OF REACTIVE EXTRACTION; PHYSICAL AND REACTIVE EXTRACTIONSOF PENICILLIN G; Equilibrium Experiments |
|
HOLLOW FIBER MEMBRANE MODULEHollow-Fiber Experiments: Effect of Solvent Type; EXTRACTIONS WITH SUNFLOWER OIL; RE-EXTRACTION (RECOVERY) OF PENICILLIN G FROM THE ORGANIC PHASE; MATHEMATICAL MODELLING OF MASS TRANSFER IN HOLLOW-FIBRE MODULE; CONCLUSION; ACKNOWLEDGMENTS; REFERENCES; CHAPTER 3. NOVEL PEPTIDE ENDOWED WITH ANTIBIOTIC PROPERTIES; ABSTRACT; INTRODUCTION; FROM THE ENZYME TO THE ABZYMEAND ITS SCFV COUNTERPART; THE PHAGE DISPLAY TECHNOLOGY: A POWERFUL TOOL TO SELECT ACTIVE BIOMOLECULES |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Penicillin.
|
|
Penicillins -- biosynthesis
|
|
Penicillins -- therapeutic use
|
|
Penicillins -- adverse effects
|
|
Penicillins
|
|
SCIENCE -- Life Sciences -- Mycology.
|
|
Penicillin
|
| Form |
Electronic book
|
| Author |
Barresi, Geneviève
|
|
Komulainen, Pere
|
| ISBN |
9781621002963 |
|
1621002969 |
|
