| Description |
1 online resource (330 pages) |
| Series |
Lecture Notes |
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Lecture Notes
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| Contents |
Clinical Pharmacology and Therapeutics : Lecture Notes; Contents; Contributors; Preface; Foreword; Part 1 Principles of clinical pharmacology; 1 Pharmacodynamics and pharmacokinetics; Introduction; Principles of drug action (pharmacodynamics); Mechanism of drug action; Action on a receptor; Action on an enzyme; Action on membrane ionic channels; Cytotoxic actions; Dose-response relationship; Principles of pharmacokinetics; Absorption; Distribution; Plasma protein binding; Clearance; Linear versus non-linear kinetics; Principles of drug elimination; Drug metabolism; Metabolic drug interactions |
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InductionInhibition; Genetic factors in metabolism; Renal excretion; 2 Clinical trials and drug development; Introduction; Drug development and regulation; Preclinical studies; Animal studies of efficacy and toxicity; Clinical trials; Phase I clinical trials; Phase II clinical trials; Phase III clinical trials; Phase IIIb and IV studies; Yellow card scheme; Translational research; Part 2 Aspects of therapeutics; 3 Drugs and gastrointestinal disease; Introduction; Gastro-oesophageal reflux disease; Relevant pathophysiology; Drugs used in the treatment of gastro-oesophageal reflux disease |
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Drugs that inhibit gastric acid secretionDrugs that act on oesophageal and/or gastric motility; Peptic ulcer; Relevant pathophysiology; Drugs used in the treatment of peptic ulcer; Drug combinations to eradicate H. pylori; Nausea and vomiting; Relevant pathophysiology; Drugs used in treatment of vomiting; Diarrhoea and constipation; Diarrhoea; Irritable bowel syndrome; Pancreatic insufficiency; Drugs used in non-specific diarrhoea; Constipation; Inflammatory bowel disease; Relevant pathophysiology; Drugs used in the treatment of inflammatory bowel disease |
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Drugs adversely affecting gastrointestinal function4 Management of coronary artery disease and its complications; Introduction; Angina pectoris and acute coronary syndromes; Aims of treatment; Relevant pathophysiology; Drugs used in angina; General principles of management of angina; Cardiac arrhythmia; Relevant pathophysiology; Classification of anti-arrhythmic drugs; Pharmacological versus non-pharmacological therapy; Class I agents; Class II agents; Class III agents; Class IV agents; Digitalis glycosides; Adenine nucleotides; Heart failure; Definition; Relevant pathophysiology |
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Neuroendocrine activation in heart failureDiuretics; Neuroendocrine antagonists; Drugs with a positive inotropic effect; Drugs affecting preload; Drugs affecting preload and afterload; General principles of management of heart failure; Long-term management of chronic heart failure; 5 Primary and secondary prevention of cardiovascular disease; Introduction; Hypertension; Relevant pathophysiology; Primary and secondary hypertension; Benefits of treatment; Principles of antihypertensive treatment; Antihypertensive drugs; Hypertensive emergencies; Cholesterol and lipids; Aim |
| Summary |
Clinical Pharmacology and Therapeutics Lecture Notes provides a clear and accessible overview of all the key prescribing topics needed for medical finals and beyond. Detailed coverage and discussion of pharmacology in a clinical context, combined with an easy-to-understand, readable style, helps improve and test understanding of pharmacological principles and reasoning on rotation and into the foundation years. Key features for this edition include: Clinical scenarios to root each chapter firmly in a real-life setting Prescribing points flagging up important issue |
| Notes |
Relevant pathophysiology |
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Print version record |
| Subject |
Therapeutics.
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Pharmacology.
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Clinical pharmacology.
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Chemotherapy.
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Pharmacological Phenomena
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Pharmacology, Clinical
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Drug Therapy
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Therapeutics
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Pharmacology
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pharmacology.
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treating (health care function)
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MEDICAL -- Pharmacology.
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Clinical pharmacology
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Chemotherapy
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Pharmacology
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Therapeutics
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| Form |
Electronic book
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| Author |
Walters, Matthew R
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| ISBN |
9781118344897 |
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1118344898 |
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