| Description |
1 online resource (ix, 137 pages) : illustrations |
| Series |
Chemical immunology ; vol. 67 |
|
Chemical immunology ; vol. 67.
|
| Contents |
Molecular mechanisms involved in T-B interactions -- Tracing antigen-driven B cell development in humans -- T cells in the selection of germinal center B cells -- Biased VH4 gene segment repertoire in the human tonsil -- Subepithelial B cells of the human tonsil -- Malignant lymphomas stem from different B cell populations -- What do chronic B cell malignancies teach us about B cell subsets? -- B cell populations: the multiple myeloma model -- Regulation of human B cell growth and differentiation: lessons from the primary immunodeficiencies |
| Summary |
B cells used to be considered as a homogeneous population of cells destined to produce antibodies of increasing affinity and to maintain an immunological memory. In recent years, it has been determined that B cells can be subdivided into different subsets characterized by distinct morphologic, phenotypic, and functional features. Presenting results of research work on the definition of B cell subset populations, this book explains the basic mechanisms that control B cell activation, stimulation and regulation. Articles include studies on both normal and malignant B cells and describe the mechanisms underlying T-B cell interactions during the immune response. The most important advances in the field of immunodeficiency are also reported. This volume will be essential not only for basic and clinical immunologists, but also for hematologists, pathologists and rheumatologists with a special interest in the pathogenesis of lymphoproliferative or autoimmune disorders |
| Bibliography |
Includes bibliographical references and indexes |
| Notes |
Current copyright fee: GBP36.40 24\0. Uk |
|
Print version record |
| Subject |
B cells -- Physiology
|
|
T cells -- Physiology
|
|
B-Lymphocytes -- physiology
|
|
T-Lymphocytes -- physiology
|
|
chemistry |
| Form |
Electronic book
|
| Author |
Ferrarini, M.
|
|
Caligaris-Cappio, Federico.
|
|
S. Karger (Firm)
|
| ISBN |
9783318002362 |
|
3318002364 |
|
