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  Proteales -- 2 Related Subjects   2
 

Protease-Activated Receptors -- See Receptors, Proteinase-Activated


A class of receptors that are activated by the action of PROTEINASES. The most notable examples are the THROMBIN RECEPTORS. The receptors contain cryptic ligands that are exposed upon the selective proteolysis of specific N-terminal cleavage sites
  1
  Protease inhibitors -- 4 Related Subjects   4
Protease inhibitors.   3
Protease Inhibitors -- metabolism.   2
 

Protease Inhibitors, Serpin -- See Serpins


A family of serine proteinase inhibitors which are similar in amino acid sequence and mechanism of inhibition, but differ in their specificity toward proteolytic enzymes. Some members of the serpin family may be substrates rather than inhibitors of SERINE ENDOPEPTIDASES
  1
Protease Inhibitors -- therapeutic use.   5
 

Protease Nexin 2 -- See Amyloid beta-Protein Precursor


A single-pass type I membrane protein. It is cleaved by AMYLOID PRECURSOR PROTEIN SECRETASES to produce peptides of varying amino acid lengths. A 39-42 amino acid peptide, AMYLOID BETA-PEPTIDES is a principal component of the extracellular amyloid in SENILE PLAQUES
  1
 

Protease Nexin II -- See Amyloid beta-Protein Precursor


A single-pass type I membrane protein. It is cleaved by AMYLOID PRECURSOR PROTEIN SECRETASES to produce peptides of varying amino acid lengths. A 39-42 amino acid peptide, AMYLOID BETA-PEPTIDES is a principal component of the extracellular amyloid in SENILE PLAQUES
  1
  Proteases -- 2 Related Subjects   2
 

Proteasome -- See Proteasome Endopeptidase Complex


A large multisubunit complex that plays an important role in the degradation of most of the cytosolic and nuclear proteins in eukaryotic cells. It contains a 700-kDa catalytic sub-complex and two 700-kDa regulatory sub-complexes. The complex digests ubiquitinated proteins and protein activated via ornithine decarboxylase antizyme
  1
 

Proteasome, 20S -- See Proteasome Endopeptidase Complex


A large multisubunit complex that plays an important role in the degradation of most of the cytosolic and nuclear proteins in eukaryotic cells. It contains a 700-kDa catalytic sub-complex and two 700-kDa regulatory sub-complexes. The complex digests ubiquitinated proteins and protein activated via ornithine decarboxylase antizyme
  1
 

Proteasome Endopeptidase Complex -- See Also Ubiquitin-Protein Ligase Complexes


Complexes of enzymes that catalyze the covalent attachment of UBIQUITIN to other proteins by forming a peptide bond between the C-terminal GLYCINE of UBIQUITIN and the alpha-amino groups of LYSINE residues in the protein. The complexes play an important role in mediating the selective-degradation of short-lived and abnormal proteins. The complex of enzymes can be broken down into three components that involve activation of ubiquitin (UBIQUITIN-ACTIVATING ENZYMES), conjugation of ubiquitin to the ligase complex (UBIQUITIN-CONJUGATING ENZYMES), and ligation of ubiquitin to the substrate protein (UBIQUITIN-PROTEIN LIGASES)
  1
Proteasome Endopeptidase Complex.   3
 

Proteasome Endopeptidase Complex antagonists & inhibitors -- See Proteasome Inhibitors


Compounds that inhibit the function or proteolytic action of the PROTEASOME
  1
 

Proteasome Endopeptidase Complex Inhibitors -- See Proteasome Inhibitors


Compounds that inhibit the function or proteolytic action of the PROTEASOME
  1
Proteasome Endopeptidase Complex -- metabolism.   2
Proteasome Endopeptidase Complex -- physiology.   3
 

Proteasome Inhibitor -- See Proteasome Inhibitors


Compounds that inhibit the function or proteolytic action of the PROTEASOME
  1
Proteasome Inhibitors.   2
Proteção ambiental. : Distributed generation : the power paradigm for the new millennium / [edited by] Anne-Marie Borbely, Jan F. Kreider  2001 1
Protect Public Art! : Protecting public art : community involement in the in the management of outdoor cultural objects / Edwina M. d'Apice  1996 1
  Protected areas -- 10 Related Subjects   10
Protected areas.   16
Protected areas -- Africa -- Management. : Framework and tools for environmental management in Africa / Godwell Nhamo & Ekpe Inyang  2011 1
Protected areas -- Africa, Southern : Transfrontier conservation areas : people living on the edge / edited by Jens A. Andersson, Michel de Garine-Wichatitsky, David H.M. Cumming, Vupenyu Dzingirai and Ken E. Giller  2017 1
Protected areas -- Asia -- Management : Asian sacred natural sites : philosophy and practice in protected areas and conservation / edited by Bas Verschuuren and Naoya Furuta  2016 1
Protected areas -- Australia.   2
Protected areas -- Australia -- Employees -- Pictorial works. : Working on country photography competition : 2010  2010 1
Protected areas -- Australia -- Management.   6
Protected areas -- Australia -- Victoria -- Castlemaine : Castlemaine Diggings National Heritage Park : draft management plan  2005 1
Protected areas -- Australia -- Victoria -- Management. : Ngootyoong Gunditj Ngootyoong Mara south west management plan / Parks Victoria  2015 1
Protected areas -- Brazil. : Tourism and protected areas in Brazil : challenges and perspectives / André de Almeida Cunha, Teresa Cristina Magro-Lindenkamp and Stephen Ford McCool, editors  2018 1
Protected areas -- Case studies.   2
Protected areas -- Classification. : Forests and protected areas : guidance on the use of the IUCN protected area management categories / Nigel Dudley and Adrian Phillips ; Adrian Phillips, series editor  2006 1
Protected areas -- Congresses.   2
Protected areas -- Developing countries -- Case studies : Protected areas, sustainable land? / edited by Catherine Aubertin and Estienne Rodary  2011 1
Protected areas -- Economic aspects.   8
Protected areas -- Economic aspects -- Malay Archipelago -- Case studies. : Biodiversity and Human Livelihoods in Protected Areas : Case Studies from the Malay Archipelago  2007 1
Protected areas -- Europe : Protected Areas and Regional Development in Europe : Towards a New Model for the 21st Century  2016 1
Protected areas -- Ghana -- Management : Adaptive management : elements, applications and research / editor, Edward D. Wiafe, Ph. D. (Department of Environment and Natural Resources, Akropong-Akuapem, Ghana)  2017 1
Protected areas -- Government policy.   2
Protected areas -- Government policy -- Malay Archipelago -- Case studies. : Biodiversity and Human Livelihoods in Protected Areas : Case Studies from the Malay Archipelago  2007 1
Protected areas -- History.   2
Protected areas -- Law and legislation   3
Protected areas -- Law and legislation -- Australia. : Terrestrial and marine protected areas in Australia (1997) / edited by I.D. Cresswell and G.M. Thomas  1997 1
Protected areas -- Law and legislation -- United States -- Periodicals. : The Wilderness Society's quarterly newsletter  2003 1
Protected areas -- Malay Archipelago -- Case studies. : Biodiversity and Human Livelihoods in Protected Areas : Case Studies from the Malay Archipelago  2007 1
Protected areas -- Management.   23
Protected areas -- Management -- Case studies.   3
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