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Book Cover
E-book

Title Long Non-Coding RNA : From Disease Biomarkers to Targeted Therapeutics / edited by Syed Mudasir Ahmad, Nazir Ahmad Ganai
Published Newcastle upon Tyne : Cambridge Scholars Publisher, 2020
©2020

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Description 1 online resource (201 pages)
Contents Functional aspects of long non-coding RNAs: a review -- Cancer development an therapy resistance: spotlight on the dark side of the genome -- Long non-coding RNAs in multiple sclerosis: an update -- Long non-coding RNAs in infection and immunity -- LncRNAs as important mediators for diagnosis, prognosis, and potential therapeutics in leukemias, Hepatocellular carcinoma, and breast cancer -- Long non-coding RNA in neurological diseases: a mechanistic insight -- Diverse functions of long non-coding RNAs in cardiovascular disease -- Regulatory mechanisms of long non-coding RNA's in host-pathogen
Summary Long non-coding RNAs (LncRNAs) were originally regarded as ""noise"" in the genome due to their lack of protein-encoding capacity. However, their roles are now understood to cover various biological functions like gene regulation, cell proliferation, survival, differentiation, and chromatin remodeling. As an emerging group of non-coding RNA molecules, LncRNAs are involved in diverse diseases like cancer, cardiovascular, autoimmune, hormonal disorders, neurodegeneration, and infection, among others. However, knowledge of the mechanisms by which they act is still ambiguous. As such, this book me
Notes Online resource; title from digital title page (viewed on December 22, 2020)
Subject Non-coding RNA.
RNA, Untranslated
Biology, life sciences.
Life sciences: general issues.
Diseases & disorders.
Non-coding RNA
Form Electronic book
Author Ahmad, Syed Mudasir, editor
Ganai, Nazir Ahmad
ISBN 1527559106
9781527559103