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Receptors, Costimulatory, T-Lymphocyte -- See Costimulatory and Inhibitory T-Cell Receptors


A family of receptors that modulate the activation of T-LYMPHOCYTES by the T-CELL ANTIGEN RECEPTOR. The receptors are responsive to one or more B7 ANTIGENS found on ANTIGEN-PRESENTING CELLS and, depending upon the specific ligand-receptor combination, modulate a variety of T-cell functions such as the rate of clonal expansion, CELL SURVIVAL and cytokine production. Although commonly referred to as costimulatory receptors, some of the receptors have inhibitory effects such as inducing PERIPHERAL TOLERANCE
  1
 

Receptors, CSF -- See Receptors, Colony-Stimulating Factor


Cell surface receptors for colony stimulating factors, local mediators, and hormones that regulate the survival, proliferation, and differentiation of hemopoietic cells
  1
Receptors, Cytokine.   5
 

Receptors, Cytokine, Common beta Chain -- See Cytokine Receptor Common beta Subunit


A receptor subunit that is a shared component of the INTERLEUKIN-3 RECEPTOR; the INTERLEUKIN-5 RECEPTOR; and the GM-CSF RECEPTOR. High affinity receptor complexes are formed with each of these receptors when their respective alpha subunits are combined with this shared beta subunit
  1
Receptors, Cytokine -- physiology.   3
 

Receptors, Cytokines -- See Receptors, Cytokine


Cell surface proteins that bind cytokines and trigger intracellular changes influencing the behavior of cells
  1
Cytokines -- Receptors.   5
 

Receptors, Cytoplasmic -- See Receptors, Cytoplasmic and Nuclear


Intracellular receptors that can be found in the cytoplasm or in the nucleus. They bind to extracellular signaling molecules that migrate through or are transported across the CELL MEMBRANE. Many members of this class of receptors occur in the cytoplasm and are transported to the CELL NUCLEUS upon ligand-binding where they signal via DNA-binding and transcription regulation. Also included in this category are receptors found on INTRACELLULAR MEMBRANES that act via mechanisms similar to CELL SURFACE RECEPTORS
  1
Receptors, Cytoplasmic and Nuclear.   11
Receptors, Cytoplasmic and Nuclear -- genetics.   2
 

Receptors, Cytoplasmic Hormone -- See Receptors, Cytoplasmic and Nuclear


Intracellular receptors that can be found in the cytoplasm or in the nucleus. They bind to extracellular signaling molecules that migrate through or are transported across the CELL MEMBRANE. Many members of this class of receptors occur in the cytoplasm and are transported to the CELL NUCLEUS upon ligand-binding where they signal via DNA-binding and transcription regulation. Also included in this category are receptors found on INTRACELLULAR MEMBRANES that act via mechanisms similar to CELL SURFACE RECEPTORS
  1
 

Receptors, Cytosol and Nuclear -- See Receptors, Cytoplasmic and Nuclear


Intracellular receptors that can be found in the cytoplasm or in the nucleus. They bind to extracellular signaling molecules that migrate through or are transported across the CELL MEMBRANE. Many members of this class of receptors occur in the cytoplasm and are transported to the CELL NUCLEUS upon ligand-binding where they signal via DNA-binding and transcription regulation. Also included in this category are receptors found on INTRACELLULAR MEMBRANES that act via mechanisms similar to CELL SURFACE RECEPTORS
  1
 

Receptors, Cytosolic and Nuclear -- See Receptors, Cytoplasmic and Nuclear


Intracellular receptors that can be found in the cytoplasm or in the nucleus. They bind to extracellular signaling molecules that migrate through or are transported across the CELL MEMBRANE. Many members of this class of receptors occur in the cytoplasm and are transported to the CELL NUCLEUS upon ligand-binding where they signal via DNA-binding and transcription regulation. Also included in this category are receptors found on INTRACELLULAR MEMBRANES that act via mechanisms similar to CELL SURFACE RECEPTORS
  1
 

Receptors, Death Domain -- See Also Receptors, Tumor Necrosis Factor


Cell surface receptors that bind TUMOR NECROSIS FACTORS and trigger changes which influence the behavior of cells
  1
Receptors, Death Domain -- physiology. : Death receptors and cognate ligands in cancer / Holger Kalthoff, ed  2009 1
 

Receptors, delta -- See Receptors, Opioid, delta


A class of opioid receptors recognized by its pharmacological profile. Delta opioid receptors bind endorphins and enkephalins with approximately equal affinity and have less affinity for dynorphins
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Receptors, delta Opioid -- See Receptors, Opioid, delta


A class of opioid receptors recognized by its pharmacological profile. Delta opioid receptors bind endorphins and enkephalins with approximately equal affinity and have less affinity for dynorphins
  1
Dendritic cells -- Receptors. : Toll and toll-like receptors : an immunologic perspective / [edited by] Tina Rich  2005 1
 

Receptors, Diazepam -- See Receptors, GABA-A


Cell surface proteins which bind GAMMA-AMINOBUTYRIC ACID and contain an integral membrane chloride channel. Each receptor is assembled as a pentamer from a pool of at least 19 different possible subunits. The receptors belong to a superfamily that share a common CYSTEINE loop
  1
 

Receptors, Dihydrotestosterone -- See Receptors, Androgen


Proteins, generally found in the CYTOPLASM, that specifically bind ANDROGENS and mediate their cellular actions. The complex of the androgen and receptor migrates to the CELL NUCLEUS where it induces transcription of specific segments of DNA
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Dopamine -- Receptors.   7
 

Receptors, Dopamine agonists -- See Dopamine Agonists


Drugs that bind to and activate dopamine receptors
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Receptors, Dopamine D2. : Pre-coupling of receptor oligomers and signaling molecules : challenging classical pharmacology / Sergi Ferré  2019 1
Receptors, Dopamine -- genetics. : Influence of neurotransmitter receptor variants on interactions with psychotropic drugs / Maria J. Arranz  2014 1
Receptors, Dopamine -- metabolism. : Brain dynamics and the striatal complex / edited by R. Miller and J.R. Wickens  2000 1
Receptors, Dopamine -- physiology.   4
 

Receptors, Drug -- See Drug receptors



--subdivision Receptors under individual drugs and groups of drugs, e.g. Insulin--Receptors
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Receptors, Drug.   5
Receptors, Drug -- agonists : Textbook of receptor pharmacology / edited by John C. Foreman, Torben Johansen  2003 1
Receptors, Drug -- antagonists & inhibitors   2
Receptors, Drug -- Periodicals : Journal of receptor research  1994 1
Receptors, Drug -- physiology.   4
 

Receptors, EGF -- See ErbB Receptors


A family of structurally-related cell-surface receptors that signal through an intrinsic PROTEIN-TYROSINE KINASE. The receptors are activated upon binding of specific ligands which include EPIDERMAL GROWTH FACTORS, and NEUREGULINS
  1
 

Receptors, Endogenous Substances -- See Receptors, Cell Surface


Cell surface proteins that bind signalling molecules external to the cell with high affinity and convert this extracellular event into one or more intracellular signals that alter the behavior of the target cell (From Alberts, Molecular Biology of the Cell, 2nd ed, pp693-5). Cell surface receptors, unlike enzymes, do not chemically alter their ligands
  1
 

Receptors, Endopeptidase-Activated -- See Receptors, Proteinase-Activated


A class of receptors that are activated by the action of PROTEINASES. The most notable examples are the THROMBIN RECEPTORS. The receptors contain cryptic ligands that are exposed upon the selective proteolysis of specific N-terminal cleavage sites
  1
 

Receptors, Endorphin -- See Receptors, Opioid


Cell membrane proteins that bind opioids and trigger intracellular changes which influence the behavior of cells. The endogenous ligands for opioid receptors in mammals include three families of peptides, the enkephalins, endorphins, and dynorphins. The receptor classes include mu, delta, and kappa receptors. Sigma receptors bind several psychoactive substances, including certain opioids, but their endogenous ligands are not known
  1
Endorphins -- Receptors.   5
Endorphins -- Receptors -- Research. : Research and development of opioid-related ligands / Mei-Chuan Ko, editor, Stephen M. Husbands, editor  2013 1
Endorphins -- Receptors -- Research -- Social aspects. : Social control and multiple discovery in science : the opiate receptor case / Susan E. Cozzens  1989 1
Receptors, Endothelin : Structure and activation of endothelin ETB receptor by endothelin / Tomoko Doi  2019 1
Endothelins -- Receptors : Structure and activation of endothelin ETB receptor by endothelin / Tomoko Doi  2019 1
 

Receptors, Enkephalin -- See Receptors, Opioid


Cell membrane proteins that bind opioids and trigger intracellular changes which influence the behavior of cells. The endogenous ligands for opioid receptors in mammals include three families of peptides, the enkephalins, endorphins, and dynorphins. The receptor classes include mu, delta, and kappa receptors. Sigma receptors bind several psychoactive substances, including certain opioids, but their endogenous ligands are not known
  1
 

Receptors, Eph -- See Receptors, Eph Family


A large family of receptor protein-tyrosine kinases that are structurally-related. The name of this family of proteins derives from original protein Eph (now called the EPHA1 RECEPTOR), which was named after the cell line it was first discovered in: Erythropoietin-Producing human Hepatocellular carcinoma cell line. Members of this family have been implicated in regulation of cell-cell interactions involved in nervous system patterning and development
  1
Receptors, Eph Family. : The Eph receptor family / Elena B. Pasquale  2007 1
 

Receptors, EphB -- See Receptors, Eph Family


A large family of receptor protein-tyrosine kinases that are structurally-related. The name of this family of proteins derives from original protein Eph (now called the EPHA1 RECEPTOR), which was named after the cell line it was first discovered in: Erythropoietin-Producing human Hepatocellular carcinoma cell line. Members of this family have been implicated in regulation of cell-cell interactions involved in nervous system patterning and development
  1
 

Receptors, Ephrin -- See Receptors, Eph Family


A large family of receptor protein-tyrosine kinases that are structurally-related. The name of this family of proteins derives from original protein Eph (now called the EPHA1 RECEPTOR), which was named after the cell line it was first discovered in: Erythropoietin-Producing human Hepatocellular carcinoma cell line. Members of this family have been implicated in regulation of cell-cell interactions involved in nervous system patterning and development
  1
 

Receptors, Ephrin A -- See Receptors, Eph Family


A large family of receptor protein-tyrosine kinases that are structurally-related. The name of this family of proteins derives from original protein Eph (now called the EPHA1 RECEPTOR), which was named after the cell line it was first discovered in: Erythropoietin-Producing human Hepatocellular carcinoma cell line. Members of this family have been implicated in regulation of cell-cell interactions involved in nervous system patterning and development
  1
 

Receptors, Epidermal Growth Factor -- See ErbB Receptors


A family of structurally-related cell-surface receptors that signal through an intrinsic PROTEIN-TYROSINE KINASE. The receptors are activated upon binding of specific ligands which include EPIDERMAL GROWTH FACTORS, and NEUREGULINS
  1
Epidermal growth factor -- Receptors. : The EGF receptor family : biologic mechanisms and role in cancer / edited by Graham Carpenter  2004 1
 

Receptors, Epidermal Growth Factor-Urogastrone -- See ErbB Receptors


A family of structurally-related cell-surface receptors that signal through an intrinsic PROTEIN-TYROSINE KINASE. The receptors are activated upon binding of specific ligands which include EPIDERMAL GROWTH FACTORS, and NEUREGULINS
  1
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