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Title Biomaterials and regenerative medicine in ophthalmology / edited by Traian V. Chirila and Damien G. Harkin
Published Duxford, UK : Woodhead Publishing is an imprint of Elsevier, 2016
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Description 1 online resource
Series Woodhead Publishing series in biomaterials ; number 112
Woodhead Publishing series in biomaterials ; no. 112
Contents Title page; Table of Contents; Related titles; Copyright; List of contributors; Woodhead Publishing Series in Biomaterials; 1. An introduction to ophthalmic biomaterials and their role in tissue engineering and regenerative medicine; 1.1. Introduction; 1.2. Development of ophthalmic biomaterials: a brief history; 1.3. Tissue engineering and regenerative medicine in ophthalmology; 1.4. Future trends; Part One. Materials, properties and considerations; 2. The ageing ocular surface: Challenges for biomaterials design and function; 2.1. Introduction; 2.2. Ageing tear film
2.3. Ageing lacrimal functional unit2.4. Compromised ocular surface and healing; 2.5. Future for biomaterials; 2.6. Challenges for biomaterials design and function; 2.7. Conclusions; 3. Ocular biotribology and the contact lens: Surface interactions and ocular response; 3.1. Introduction; 3.2. Coefficient of friction; 3.3. Significance of contact lens and ocular surface interactions; 3.4. Coefficient of friction of contact lenses: material and subject-related variables; 3.5. Future trends and conclusions; 4. Physicochemical properties of hydrogels for use in ophthalmology; 4.1. Introduction
4.2. Water in hydrogels: effects of monomer structure4.3. Effect of hydrogel water content on properties; 4.4. Modified hydrogels; 5. Current concepts in the design of hydrogels as vitreous substitutes; 5.1. Introduction; 5.2. Vitreous humor; 5.3. Design of vitreous substitutes; 5.4. Conclusions and recommendations; 5.5. Future trends; 6. Biomaterials for intraocular sustained drug delivery; 6.1. Introduction; 6.2. Anatomical and physiological specificities of the eye; 6.3. Challenging vitreoretinal diseases and targeted molecules; 6.4. Nonbiodegradable devices; 6.5. Biodegradable devices
6.6. Triamcinolone acetonide crystal suspension6.7. Renexus®: encapsulated cell technology; 6.8. Gelling agents; 6.9. Conclusions and future trends; List of abbreviations; Part Two. Biomaterials for the repair and regeneration of the cornea and ocular surface; 7. Collagen scaffolds for corneal regeneration; 7.1. Introduction; 7.2. Scaffolds derived from decellularized stroma; 7.3. Scaffolds fabricated from polymerized collagen; 7.4. Scaffolds fabricated by cells: the true bottom-up approach; 7.5. Populating the scaffolds; 7.6. Future trends
8. Reconstruction of the ocular surface using biomaterial templates8.1. Introduction; 8.2. Treatment of ocular surface disorders; 8.3. Ex vivo expansion of ocular surface epithelial cells; 8.4. Corneal equivalents as replacements or study models; 8.5. Naturally derived biomaterials as substrata for tissue-engineered epithelial constructs; 8.6. Synthetic biomaterials as substrata for tissue-engineered epithelial constructs; 8.7. Strategies based on thermoresponsive polymers; 8.8. Evaluation of silk proteins as substratum for human limbal epithelial cells; 8.9. Conclusions
Notes Includes index
Online resource; title from PDF title page (ScienceDirect, viewed May 9, 2016)
Subject Ophthalmology.
Regenerative medicine.
Form Electronic book
Author Chirila, Traian, editor
Harkin, Damien, editor
ISBN 0081001843 (electronic bk)
9780081001844 (electronic bk)
(print)