| Description |
1 online resource (xvi, 441 pages) : illustrations (some color) |
| Series |
Recent advances in human biology ; v. 10 |
|
Recent advances in human biology ; v. 10.
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| Contents |
Foreword -- Ch. 1 Cell biology of photoreceptors and the RPE: a brief introduction / David S. Williams -- Ch. 2 Crumbs-dependent epithelial organization in retinal morphogenesis and disease / Donald F. Ready and Ulrich Tepass -- Ch. 3 From the golgi to the rod outer segment: formation, movement, docking and fusion of rhodopsin transport carriers / Dusanka Deretic -- Ch. 4 Insights on retinal degeneration: molecular basis of polarized rhodopsin transport / Ching-Hwa Sung and Jen-Zen Chuang -- Ch. 5 Targeting of visual pigments to rod outer segment in rhodopsin knockout mice / Guang Shi, Francis A. Concepcion and Jeannie Chen -- Ch. 6 Photoreceptors and intraflagellar transport / Sheila A. Baker, Gregory J. Pazour, George B. Witman and Joseph C. Besharse -- Ch. 7 Myosin III in receptors: what does it do? / Andréa Dosé, Jennifer Lin-Jones and Beth Burnside -- Ch. 8 Light-dependent translocation of signaling proteins in vertebrate and invertebrate photoreceptors / Katherine J. Strissel, Maxim Sokolov and Vadim Y. Arshavsky -- Ch. 9 Centrins, potential regulators of transducin translocation in photoreceptor cells / Andreas Giessl, Philipp Trojan, Alexander Pulvermüller and Uwe Wolfrum -- Ch. 10 The RP1 gene and protein in photoreceptor biology / Sara Achenbach, Qin Liu and Eric A. Pierce -- Ch. 11 Molecular organization of rod outer segments / Robert S. Molday -- Ch. 12 Biochemistry and cell biology of the visual cycle / John C. Saari -- Ch. 13 Role of Mertk in RPE phagocytosis and retinal disease / Douglas Vollrath and Wei Feng -- Ch. 14 Roles of integrin receptors in the daily phagocytosis of photoreceptor outer segment fragments by the RPE / Emeline F. Nandrot and Silvia C. Finnemann -- Ch. 15 Myosin VIIa in the retina / David S. Williams and Daniel Gibbs -- Index |
| Summary |
This important book presents review articles on the cell biology of photoreceptor and RPE cells, as well as the relationship between this cell biology and inherited photoreceptor degeneration. The chapters have been written by leaders in the field. The vision scientist will see this book as a review of photoreceptor and RPE cell biology, and known molecular bases of many forms of retinitis pigmentosa and related retinal degeneration. For the cell biologist, there are articles on topics such as protein targeting, molecular motors, and phagocytosis placed in the functional context of two of the most specialized cells in the body |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Retina -- Diseases -- Molecular aspects
|
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Retina -- Cytology.
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Retinal Degeneration -- physiopathology
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Photoreceptors -- physiology
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Molecular Biology
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MEDICAL -- Ophthalmology.
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HEALTH & FITNESS -- Vision.
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Retina -- Cytology
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| Form |
Electronic book
|
| Author |
Williams, David S.
|
| ISBN |
9812561757 |
|
9789812561756 |
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