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Signal Transduction -- See Also Ion Channels


Gated, ion-selective glycoproteins that traverse membranes. The stimulus for ION CHANNEL GATING can be due to a variety of stimuli such as LIGANDS, a TRANSMEMBRANE POTENTIAL DIFFERENCE, mechanical deformation or through INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS
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Signal Transduction.   196
 

Signal transduction, Cellular -- See Cellular signal transduction


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Signal Transduction -- drug effects.   5
Signal Transduction -- genetics.   5
Signal Transduction -- immunology.   5
 

Signal Transduction, Mechanical -- See Mechanotransduction, Cellular


The process by which cells convert mechanical stimuli into a chemical response. It can occur in both cells specialized for sensing mechanical cues such as MECHANORECEPTORS, and in parenchymal cells whose primary function is not mechanosensory
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Signal Transduction -- metabolism : Integrated view on a eukaryotic osmoregulation system / Stefan Hohmann  2014 1
 

Signal Transduction Pathway -- See Signal Transduction


The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway
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Signal Transduction Pathways -- See Signal Transduction


The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway
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Signal Transduction -- Periodicals   2
Signal Transduction -- physiology.   65
Signal Transduction -- radiation effects. : Molecular determinants of radiation response / Theodore L. DeWeese, Marikki Laiho, Editors  2011 1
 

Signal Transduction, Receptor-Mediated -- See Signal Transduction


The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway
  1
 

Signal Transduction System -- See Signal Transduction


The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway
  1
 

Signal Transduction Systems -- See Signal Transduction


The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway
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Signal Transductions -- See Signal Transduction


The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway
  1
 

Signal Transductions, Receptor-Mediated -- See Signal Transduction


The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway
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Signalbehandling.   3
Australia. Australian Army http://id.loc.gov/authorities/names/n79095437 -- Signaling : The saga of a Sig : the wartime memories of six years service in the second A.I.F. / by Ken Clift  1972 1
Australia. Australian Army http://id.loc.gov/authorities/names/n79095437 -- Signaling -- History : Signals : story of the Australian Corps of Signals / written and prepared by members of the Australian Corps of Signals  1951 1
 

Signaling, Calcium -- See Calcium Signaling


Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes, sparks, or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins
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Signaling, Internet telephony -- See Internet telephony Signaling


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Internet telephony -- Signaling. : Measuring SIP proxy server performance / Sureshkumar V. Subramanian, Rudra Dutta  2013 1
 

Signaling, Paracrine -- See Paracrine Communication


Cellular signaling in which a factor secreted by a cell affects other cells in the local environment. This term is often used to denote the action of INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS on surrounding cells
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Signaling pathway, JAK-STAT -- See JAK-STAT pathway


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Signaling Pathway, JNK -- See MAP Kinase Signaling System


An intracellular signaling system involving the MAP kinase cascades (three-membered protein kinase cascades). Various upstream activators, which act in response to extracellular stimuli, trigger the cascades by activating the first member of a cascade, MAP KINASE KINASE KINASES; (MAPKKKs). Activated MAPKKKs phosphorylate MITOGEN-ACTIVATED PROTEIN KINASE KINASES which in turn phosphorylate the MITOGEN-ACTIVATED PROTEIN KINASES; (MAPKs). The MAPKs then act on various downstream targets to affect gene expression. In mammals, there are several distinct MAP kinase pathways including the ERK (extracellular signal-regulated kinase) pathway, the SAPK/JNK (stress-activated protein kinase/c-jun kinase) pathway, and the p38 kinase pathway. There is some sharing of components among the pathways depending on which stimulus originates activation of the cascade
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Signaling Pathway, Wnt -- See Wnt Signaling Pathway


A complex signaling pathway whose name is derived from the DROSOPHILA Wg gene, and the vertebrate INT gene. The signaling pathway is initiated by the binding of WNT PROTEINS to cell surface WNT RECEPTORS which interact with the AXIN SIGNALING COMPLEX and an array of second messengers that influence the actions of BETA CATENIN
  1
 

Signaling Pathways, JNK -- See MAP Kinase Signaling System


An intracellular signaling system involving the MAP kinase cascades (three-membered protein kinase cascades). Various upstream activators, which act in response to extracellular stimuli, trigger the cascades by activating the first member of a cascade, MAP KINASE KINASE KINASES; (MAPKKKs). Activated MAPKKKs phosphorylate MITOGEN-ACTIVATED PROTEIN KINASE KINASES which in turn phosphorylate the MITOGEN-ACTIVATED PROTEIN KINASES; (MAPKs). The MAPKs then act on various downstream targets to affect gene expression. In mammals, there are several distinct MAP kinase pathways including the ERK (extracellular signal-regulated kinase) pathway, the SAPK/JNK (stress-activated protein kinase/c-jun kinase) pathway, and the p38 kinase pathway. There is some sharing of components among the pathways depending on which stimulus originates activation of the cascade
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Signaling Pathways, Wnt -- See Wnt Signaling Pathway


A complex signaling pathway whose name is derived from the DROSOPHILA Wg gene, and the vertebrate INT gene. The signaling pathway is initiated by the binding of WNT PROTEINS to cell surface WNT RECEPTORS which interact with the AXIN SIGNALING COMPLEX and an array of second messengers that influence the actions of BETA CATENIN
  1
 

Signaling Peptides, Intracellular -- See Intracellular Signaling Peptides and Proteins


Proteins and peptides that are involved in SIGNAL TRANSDUCTION within the cell. Included here are peptides and proteins that regulate the activity of TRANSCRIPTION FACTORS and cellular processes in response to signals from CELL SURFACE RECEPTORS. Intracellular signaling peptide and proteins may be part of an enzymatic signaling cascade or act through binding to and modifying the action of other signaling factors
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Signaling Proteins, Intracellular -- See Intracellular Signaling Peptides and Proteins


Proteins and peptides that are involved in SIGNAL TRANSDUCTION within the cell. Included here are peptides and proteins that regulate the activity of TRANSCRIPTION FACTORS and cellular processes in response to signals from CELL SURFACE RECEPTORS. Intracellular signaling peptide and proteins may be part of an enzymatic signaling cascade or act through binding to and modifying the action of other signaling factors
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Railroads -- Signaling.   2
Railroads -- Signaling -- Congresses. : Seminars at the G-MEX Exhibition and Event Centre, Manchester : Mainline railways, Tuesday, 29 September 1998 ; Signalling issues, Wednesday, 30 September 1998 ; Light rail transit, Thursday, 1 October 1998 : delegate information / organised by Thomas Telford Conferences on behalf of the Transport Board of the Institution of Civil Engineers and the Institution of Railway Signal Engineers in conjunction with the Infrarail 98 International Exhibition organised by Mack Brooks Exhibitions Ltd, 29 September-1 October 1998, Central Hall, G-MEX Exhibition and Event Centre, Manchester  2011 1
 

Signaling Regulators, G-Protein -- See GTP-Binding Protein Regulators


Proteins that regulate the signaling activity of GTP-BINDING PROTEINS. They are divided into three categories depending upon whether they stimulate GTPase activity (GTPASE-ACTIVATING PROTEINS), inhibit release of GDP; (GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS); or exchange GTP for GDP; (GUANINE NUCLEOTIDE EXCHANGE FACTORS)
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Signaling system 7. : Developments in telecommunications : with a focus on SS7 network reliability / Gerhard Rufa  2008 1
Signaling system 7 -- Reliability. : Developments in telecommunications : with a focus on SS7 network reliability / Gerhard Rufa  2008 1
 

Signalings, Calcium -- See Calcium Signaling


Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes, sparks, or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins
  1
 

Signalings, Paracrine -- See Paracrine Communication


Cellular signaling in which a factor secreted by a cell affects other cells in the local environment. This term is often used to denote the action of INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS on surrounding cells
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Signalized intersections. : Kooperative Verkehrsbeeinflussung und Verkehrssteuerung an signalisierten Knotenpunkten / Thomas Otto  2011 1
Signals. : Strategic Effects of the Conflict with Iraq: Latin America  2003 1
TECHNOLOGY & ENGINEERING -- Signals & Signal Processing.   5
  Signals and signaling -- 8 Related Subjects   8
Signals and signaling   13
Signals and signaling -- Australia -- Design and construction -- History -- Juvenile literature. : Cables and signals : communications structures / Robert Hillman  2007 1
Signals and signaling, Automobile. : Automotive lighting and human vision / Burkard W├Ârdenweber [and others]  2007 1
Signals and signaling -- Law and legislation -- Europe. : SIGNI : signs and signals on inland waterways / Economic Commission for Europe, Inland Transport Committee, Working Party on Inland Water Transport  2005 1
Signals and signaling -- Mathematical models   4
Signals and signaling -- Periodicals : Signals (Washington, D.C. : 1950)  1950- 1
  Signals and signaling, Submarine -- 2 Related Subjects   2
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