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E-book

Title Adverse cutaneous drug eruptions / volume editor, Lars E. French
Published Basel, Switzerland ; New York : Karger, ©2012

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Description 1 online resource (xiv, 240 pages) : illustrations (some color)
Series Chemical immunology and allergy, 1660-2442 ; v. 97
Chemical immunology and allergy ; v. 97. 1660-2242
Contents Cover -- Contents -- Preface -- Epidemiology of Cutaneous Adverse Drug Reactions -- Abstract -- Essentials in a Nutshell -- Introduction -- Clinical Pattern of Cutaneous Adverse Drug Reactions -- Epidemiologic Studies on Cutaneous Adverse Drug Reactions -- Epidemiologic Studies on Severe Cutaneous Adverse Reaction -- Etiology of Cutaneous Adverse Drug Reactions -- Etiology and Medication Risk of Severe Cutaneous Adverse Reaction -- Genetic Epidemiology on Cutaneous Adverse Drug Reactions -- References
Genetics and the Potential for Predictive Tests in Adverse Drug ReactionsAbstract -- Essentials in a Nutshell -- Introduction -- Investigation into the Genetics of Cutaneous Drug Eruption -- Genetic Predisposing Factors for Cutaneous Adverse Drug Reactions -- Conclusions and Future Perspectives -- Acknowledgements -- References -- Etiology and Pathogenesis of Adverse Drug Reactions -- Abstract -- Essentials in a Nutshell -- Introduction -- Pathogenesis -- Conclusion -- References -- Diagnostic Approach to Drug Allergy -- Abstract
""Essentials in a Nutshell""""Introduction""; ""Diagnostic Approach for Selected Types of Adverse Cutaneous Drug Reactions""; ""Diagnostic Approach in Hypersensitivity Reactions to Selected Substances""; ""References""; ""Histopathological Patterns Indicative of Distinct Adverse Drug Reactions""; ""Abstract""; ""Essentials in a Nutshell""; ""Drug Reactions with Superficial and Deep Dermal Infiltrates""; ""Drug Reactions with Predominant Cytotoxic Epidermal Changes""; ""Lichenoid Pattern � Lichen Planus- Like Reactions""; ""Spongiotic Pattern""; ""Granulomatous Pattern""
Vasculitic PatternPsoriasiform Pattern -- Neutrophilic Drug Reactions -- Vesiculobullous Drug Reactions -- Panniculitis Induced by Drugs -- Folliculitis -- Sclerodermoid Drug Reactions -- References -- Uncomplicated Drug-Induced Disseminated Exanthemas -- Abstract -- Essentials in a Nutshell -- Introduction -- Morphology -- Localization, Distribution, and Evolution -- Chronology -- Etiology -- Pathophysiology -- Special Manifestations of Benign or Uncomplicated Drug Exanthemas -- Differential Diagnosis -- Diagnostic Procedures
Therapeutic OptionsReferences -- Drug-Induced Angioedema -- Abstract -- Essentials in a Nutshell -- Introduction -- Types of Angioedema -- Drug-Induced Angioedema -- Diagnostics and Treatment -- Conclusions -- References -- Fixed Drug Eruption: The Dark Side of Activation of Intraepidermal CD8+ T Cells Uniquely Specialized to Mediate Protective Immunity -- Abstract -- Essentials in a Nutshell -- Introduction -- Clinical Manifestations of Fixed Drug Eruption -- Unusual Forms of Fixed Drug Eruption -- Histology of Fixed Drug Eruption
Summary "The skin is one of the most frequently involved organs in adverse drug reactions. Occurring with an incidence of 1 to 5 percent for certain types of drugs, cutaneous drug eruptions are mostly benign in nature, and comprise the maculopapular type of eruption and urticaria. However, about one third of them require hospital treatment, leading to a considerable burden for the health care system. In this book, a selected group of experts provide an up-to-date, condensed and clinically relevant overview of the field of cutaneous drug eruptions, ranging from epidemiology and genetic predisposition to available therapeutic measures, including rapid drug desensitization. Reflecting the great progress made in recent years in this field, this publication will be a useful tool for a better understanding, diagnosis and management of cutaneous drug eruptions, not only for general physicians, dermatologists and clinical allergologists, but also for nurses and scientists."--Publisher's site
Bibliography Includes bibliographical references and indexes
Notes Print version record
Subject Drug-exanthems.
Drugs -- Side effects.
Drug allergy.
Drug Eruptions
Drug Hypersensitivity
Drug Hypersensitivity -- complications
Drug-Related Side Effects and Adverse Reactions
Skin Diseases -- chemically induced
MEDICAL -- Pharmacology.
Drug allergy
Drug-exanthems
Drugs -- Side effects
Form Electronic book
Author French, Lars E
ISBN 9783805599719
3805599714