| Description |
1 online resource |
| Series |
Advances in experimental medicine and biology ; 774 |
|
Advances in experimental medicine and biology ; 774.
|
| Contents |
MicroRNAs in Human Cancer / Thalia A. Farazi, Jessica I. Hoell, Pavel Morozov -- Bioinformatics, Non-coding RNAs and Its Possible Application in Personalized Medicine / Simona Rossi Ph. D., George A. Calin M.D., Ph. D. -- MicroRNA Target Prediction and Validation / William Ritchie, John E.J. Rasko, Stéphane Flamant -- MicroRNA-Regulated Networks: The Perfect Storm for Classical Molecular Biology, the Ideal Scenario for Systems Biology / Julio Vera, Xin Lai, Ulf Schmitz, Olaf Wolkenhauer -- The p53/microRNA Network in Cancer: Experimental and Bioinformatics Approaches / Sabine Hünten, Helge Siemens, Markus Kaller -- MicroRNAs in Melanoma Biology / Manfred Kunz M.D. -- MicroRNAs in the Lung / Alexandra Sittka, Bernd Schmeck -- The E2F1-miRNA Cancer Progression Network / Susanne Knoll, Stephan Emmrich, Brigitte M. Pützer -- Modeling microRNA-Transcription Factor Networks in Cancer / Baltazar D. Aguda -- Coordinated Networks of microRNAs and Transcription Factors with Evolutionary Perspectives / Hisakazu Iwama M.D., D. Med. Sci. -- Mathematical Modeling of microRNA-Mediated Mechanisms of Translation Repression / Andrei Zinovyev, Nadya Morozova, Alexander N. Gorban -- Web Resources for microRNA Research / Ulf Schmitz, Olaf Wolkenhauer -- Discovery of microRNA Regulatory Networks by Integrating Multidimensional High-Throughput Data / Jian-Hua Yang, Liang-Hu Qu -- Discovering Functional microRNA-mRNA Regulatory Modules in Heterogeneous Data / Bing Liu, Lin Liu, Anna Tsykin, Gregory J. Goodall -- Elucidating the Role of microRNAs in Cancer Through Data Mining Techniques / Luciano Cascione, Alfredo Ferro, Rosalba Giugno -- Working Together: Combinatorial Regulation by microRNAs / Yitzhak Friedman, Ohad Balaga, Michal Linial |
| Summary |
This book reflects the current state of knowledge about the role of microRNAs in the formation and progression of solid tumours. The main focus lies on computational methods and their applications in combination with cutting edge experimental techniques that are used to approach all aspects of microRNA regulation in cancer. The use of high-throughput quantitative techniques makes an integrative experimental and computational approach necessary. This book will be a resource for researchers starting out with microRNA research, but is also intended for the experienced researcher who wants to incorporate concepts and tools from systems biology and bioinformatics into his work. Bioinformaticians and modellers are provided with a general perspective on microRNA biology, and the state-of-the-art in computational microRNA biology |
| Bibliography |
Cludes bibliographical references |
| Notes |
Print version record |
| Subject |
Small interfering RNA -- Research
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Cancer -- Genetic aspects -- Research
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Genomics -- Data processing
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Bioinformatics.
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Computational biology.
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MicroRNA.
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MicroRNAs
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Neoplasms -- genetics
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Computational Biology -- methods
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Computational Biology
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HEALTH & FITNESS -- Diseases -- Cancer.
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MEDICAL -- Oncology.
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MicroRNA
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Computational biology
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Bioinformatics
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Cancer -- Genetic aspects -- Research
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Genomics -- Data processing
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| Form |
Electronic book
|
| Author |
Schmitz, Ulf.
|
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Wolkenhauer, Olaf, 1966-
|
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Vera, Julio.
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| ISBN |
9789400755901 |
|
9400755902 |
|
9781299407657 |
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129940765X |
|
