| Description |
1 online resource (370 pages) : illustrations |
| Series |
BIOSCIENCEnetBASE
|
| Contents |
The Building Blocks of the Complement System, D. Morikis and J. D. Lambris; Complement Control Protein Modules in the Regulators of Complement Activation, D. C. Soares and P. N. Barlow; The Classical Pathway C1 Complex, G. J. Arlaud, C. Gaboriaud, N. M. Thielens, L. A. Gregory, J. Juanhuix, V. Rossi, and J. C. Fontecilla-Camps; Factors D and B: Substrate-Inducible Serine Proteases of the Alternative Pathway of Complement Activation, Yuanyuan Xu, Karthe Ponnuraj, Sthanam V. L. Narayana, and John E. Volanakis; The Structures of Human Complement Fragments C3d and C4Ad and the Functional Insights That They Have Provided, D. E. Isenman and J. M. H. van den Elsen; Complement Receptor CR2/CD21 and CR2-C3d Complexes, J. P. Hannan, G. Szakonyi, R. Asokan, X. Chen, and V. M. Holers; Structure of the Anaphylatoxins C3a and C5a, D. Morikis, M. C. H. Holland, and J. D. Lambris; C3b/C4b Binding Site of Complement Receptor Type 1 (CR1, CD35), M. Krych-Goldberg, P. N. Barlow, R. L. Mallin, and J. P. Atkinson; From Structure to Function of a Complement Regulator; Decay-Accelerating Factor (CD55), P. Lukacik, P. Roversi, R. A. G. Smith, and S. M. Lea; Complement Protein C8, L. Lebioda and J. M. Sodetz; Structure-Function Relationships in CD59, B. P. Morgan and S. Tomlinson; Complement-like Repeats in Proteins of the Complement System, K. Dolmer and P. G. W. Gettins; Complement and Immunoglobulin Protein Structures by X-Ray and Neutron Solution Scattering and Analytical Ultracentrifugation, S. J. Perkins and B. Furtado; Structure, Dynamics, Activity, and Function of Compstatin and Design of More Potent Analogues; D. Morikis and J. D. Lambris; Discovery of Potent Cyclic Antagonists of Human C5a Receptors, S. M. Taylor and D. P. Fairlie |
| Summary |
"Structural Biology of the Complement System is devoted to the full exploration of structural aspects of the complement system, with special consideration of the links between molecular structure and function." "Containing the work of leading authorities across the disciplines of immunology and structural biology, the book serves as both an introductory volume for newcomers to the field and as a comprehensive reference for established researchers, in particular those whose goal is the discovery of anticomplement drugs. Written in a didactic style, this volume is an appropriate resource for students in the fields of immunology and structural biology."--Jacket |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Complement (Immunology) -- Structure
|
|
Complement System Proteins -- immunology
|
|
MEDICAL -- Immunology.
|
| Form |
Electronic book
|
| Author |
Lambris, J. D. (John D.)
|
|
Morikis, Dimitrios
|
| LC no. |
2004058265 |
| ISBN |
0849350360 |
|
9780849350368 |
|
